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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

65 hedge funds and large institutions have $40.8M invested in Syros Pharmaceuticals, Inc. Common Stock in 2024 Q3 according to their latest regulatory filings, with 12 funds opening new positions, 11 increasing their positions, 15 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed

7% less funds holding

Funds holding: 7065 (-5)

27% less repeat investments, than reductions

Existing positions increased: 11 | Existing positions reduced: 15

29% less first-time investments, than exits

New positions opened: 12 | Existing positions closed: 17

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

61% less capital invested

Capital invested by funds: $105M → $40.8M (-$64.4M)

90% less call options, than puts

Call options by funds: $281K | Put options by funds: $2.73M

Holders
65
Holders Change
-5
Holders Change %
-7.14%
% of All Funds
0.93%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.01%
New
12
Increased
11
Reduced
15
Closed
17
Calls
$281K
Puts
$2.73M
Net Calls
-$2.45M
Net Calls Change
-$2.58M
Name Holding Trade Value Shares
Change
Change in
Stake
BCLSI
1
Bain Capital Life Sciences Investors
Massachusetts
$5.91M +$1.23K +343 +0%
SL
2
Siren LLC
Connecticut
$5.56M +$9.29M +2,587,372 New
Adage Capital Partners
3
Adage Capital Partners
Massachusetts
$4.45M
SB
4
Samsara BioCapital
California
$3.84M
Point72 Asset Management
5
Point72 Asset Management
Connecticut
$3.16M
FP
6
Flagship Pioneering
Massachusetts
$2.78M
APM
7
Avidity Partners Management
Texas
$2.29M -$2.19M -610,538 -36%
Vanguard Group
8
Vanguard Group
Pennsylvania
$2.05M -$53.5K -14,904 -2%
DTC
9
Deep Track Capital
Connecticut
$1.78M
OM
10
Opaleye Management
Massachusetts
$1.41M -$756K -210,500 -24%
BOCH
11
Blue Owl Capital Holdings
New York
$1.11M +$629K +175,000 +51%
UOC
12
UBS O'Connor
Illinois
$773K +$292K +81,202 +29%
ECM
13
ExodusPoint Capital Management
New York
$673K +$177K +49,313 +19%
EAM
14
Exome Asset Management
New York
$642K +$501K +139,400 +88%
BlackRock
15
BlackRock
New York
$562K +$8.58K +2,390 +0.9%
OFM
16
Omega Fund Management
Massachusetts
$540K
Geode Capital Management
17
Geode Capital Management
Massachusetts
$440K -$76.9K -21,415 -9%
Marshall Wace
18
Marshall Wace
United Kingdom
$345K
PA
19
Perceptive Advisors
New York
$251K
Renaissance Technologies
20
Renaissance Technologies
New York
$207K -$75.4K -21,000 -18%
PCM
21
Prelude Capital Management
New York
$192K +$175K +48,800 +121%
Walleye Capital
22
Walleye Capital
New York
$186K -$715K -199,162 -70%
Qube Research & Technologies (QRT)
23
Qube Research & Technologies (QRT)
United Kingdom
$167K +$178K +49,557 +176%
State Street
24
State Street
Massachusetts
$149K
Acadian Asset Management
25
Acadian Asset Management
Massachusetts
$113K +$65.7K +18,288 +53%

SYRS Hedge Fund Activity: Q3 2024 in Review

65 of the 6,964 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q3 2024, worth a combined $40.8M — down 61% from $105M a quarter earlier.

Sellers outnumbered buyers: 17 funds closed out of SYRS and 12 opened new positions — a net loss of 5 holders — while 15 trimmed existing stakes and 11 added.

The largest buyer was Blue Owl Capital Holdings, adding an estimated $629K. The largest seller was Artal Group, exiting entirely with an estimated $12.9M sold.

  • 65 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q3 2024, down from 70 in Q2 2024.
  • Funds reported $40.8M of Syros Pharmaceuticals, Inc. Common Stock stock for Q3 2024, down 61% quarter-over-quarter.
  • 12 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q3 2024 and 17 closed out, a net change of -5 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q3 2024 was Blue Owl Capital Holdings, an estimated $629K added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q3 2024 was Artal Group, an estimated $12.9M sold.

Based on aggregated 13F filings for Q3 2024.