BBA

Baker Bros. Advisors Portfolio holdings

AUM $17.4B
1-Year Est. Return 131.5%
This Fund
S&P 500
This Quarter Est. Return
1 Year Est. Return
+131.5%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$17.4B
AUM Growth
+$337M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
93
New
Increased
Reduced
Closed

Top Buys

1
+$194M
2
+$151M
3
+$127M
4
MIRM icon
Mirum Pharmaceuticals
MIRM
+$42M
5
CRNX icon
Crinetics Pharmaceuticals
CRNX
+$31.4M

Top Sells

1
+$63.8M
2
+$51.4M
3
+$38.4M
4
BNTX icon
BioNTech
BNTX
+$25.6M
5
BCRX icon
BioCryst Pharmaceuticals
BCRX
+$22M

Sector Composition

1 Healthcare 99.57%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
CRNX icon
26
Crinetics Pharmaceuticals
CRNX
$3.75B
$85.4M 0.49%
2,351,465
+702,596
REPL icon
27
Replimune Group
REPL
$718M
$84.5M 0.49%
11,045,336
NRIX icon
28
Nurix Therapeutics
NRIX
$1.84B
$72.2M 0.41%
4,658,556
DNLI icon
29
Denali Therapeutics
DNLI
$3.34B
$71.6M 0.41%
3,731,695
DNTH icon
30
Dianthus Therapeutics
DNTH
$5.08B
$71.5M 0.41%
852,164
+62,405
GLUE icon
31
Monte Rosa Therapeutics
GLUE
$1.67B
$71.5M 0.41%
4,345,736
GPCR icon
32
Structure Therapeutics
GPCR
$2.8B
$69M 0.4%
1,432,529
TRDA icon
33
Entrada Therapeutics
TRDA
$274M
$64M 0.37%
5,072,730
BCYC
34
Bicycle Therapeutics
BCYC
$327M
$50.5M 0.29%
10,885,357
SYRE icon
35
Spyre Therapeutics
SYRE
$6.38B
$50.4M 0.29%
1,000,000
RAPP
36
Rapport Therapeutics
RAPP
$1.89B
$48.4M 0.28%
1,547,090
ALMS
37
Alumis Inc
ALMS
$2.75B
$44.3M 0.25%
2,012,500
+450,000
MIRM icon
38
Mirum Pharmaceuticals
MIRM
$6.19B
$41.2M 0.24%
+445,975
VRDN icon
39
Viridian Therapeutics
VRDN
$1.95B
$38.6M 0.22%
1,971,678
ELVN icon
40
Enliven Therapeutics
ELVN
$2.41B
$35.5M 0.2%
905,191
+633,785
PRLD icon
41
Prelude Therapeutics
PRLD
$312M
$34.6M 0.2%
10,123,824
DBVT
42
DBV Technologies
DBVT
$1.13B
$30.5M 0.18%
1,461,425
DSGN icon
43
Design Therapeutics
DSGN
$655M
$27.5M 0.16%
2,585,978
+352,879
CNTA
44
Centessa Pharmaceuticals
CNTA
$6.15B
$26.6M 0.15%
670,751
CTMX icon
45
CytomX Therapeutics
CTMX
$784M
$23.4M 0.13%
4,975,826
+725,000
JBIO
46
Jade Biosciences
JBIO
$1.04B
$23.1M 0.13%
1,641,137
IRON icon
47
Disc Medicine
IRON
$2.66B
$22.4M 0.13%
349,657
+12,607
IMCR icon
48
Immunocore
IMCR
$1.47B
$22.1M 0.13%
734,397
-1,588,259
XENE icon
49
Xenon Pharmaceuticals
XENE
$5.29B
$21.5M 0.12%
370,208
CLDX icon
50
Celldex Therapeutics
CLDX
$2.47B
$21.1M 0.12%
665,370
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