BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+11.22%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$10.3B
AUM Growth
+$10.3B
Cap. Flow
+$826M
Cap. Flow %
8.01%
Top 10 Hldgs %
81.62%
Holding
101
New
12
Increased
23
Reduced
8
Closed
11

Top Buys

1
INSM icon
Insmed
INSM
$235M
2
SMMT icon
Summit Therapeutics
SMMT
$198M
3
ALKS icon
Alkermes
ALKS
$55.1M
4
RVMD icon
Revolution Medicines
RVMD
$52.5M
5
GPCR icon
Structure Therapeutics
GPCR
$44.5M

Top Sells

1
CRSP icon
CRISPR Therapeutics
CRSP
$22.3M
2
ARGX icon
argenx
ARGX
$22M
3
CNTA
Centessa Pharmaceuticals
CNTA
$17.6M
4
TSVT
2seventy bio
TSVT
$12.3M
5
AKRO icon
Akero Therapeutics
AKRO
$12M

Sector Composition

1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
TECX
76
Tectonic Therapeutic, Inc. Common Stock
TECX
$328M
$1.99M 0.02%
100,000
– –
CADL icon
77
Candel Therapeutics
CADL
$297M
$1.8M 0.02%
355,112
-2,082,077
-85% -$10.5M
TARA icon
78
Protara Therapeutics
TARA
$127M
$1.63M 0.02%
536,832
– –
VTVT icon
79
vTv Therapeutics
VTVT
$48.2M
$1.46M 0.01%
97,314
– –
RCKT icon
80
Rocket Pharmaceuticals
RCKT
$364M
$1.35M 0.01%
552,079
-545,000
-50% -$1.34M
CTNM
81
Contineum Therapeutics
CTNM
$314M
$1.24M 0.01%
312,500
– –
HOOK
82
DELISTED
HOOKIPA Pharma
HOOK
$1.02M 0.01%
812,814
– –
NMRA icon
83
Neumora Therapeutics
NMRA
$290M
$759K 0.01%
1,034,600
– –
GBIO icon
84
Generation Bio
GBIO
$41M
$623K 0.01%
1,944,945
– –
ALGS icon
85
Aligos Therapeutics
ALGS
$74.3M
$599K 0.01%
83,055
– –
TYRA icon
86
Tyra Biosciences
TYRA
$690M
$102K ﹤0.01%
10,607
– –
ACRV icon
87
Acrivon Therapeutics
ACRV
$43.1M
$27.1K ﹤0.01%
22,809
– –
SRZNW icon
88
Surrozen, Inc. Warrant
SRZNW
$71.9K
$15.1K ﹤0.01%
833,333
– –
CMPX icon
89
Compass Therapeutics
CMPX
$478M
– –
-547,498
Closed -$1.04M
CNTA
90
Centessa Pharmaceuticals
CNTA
$2.28B
– –
-1,227,178
Closed -$17.6M
CRSP icon
91
CRISPR Therapeutics
CRSP
$4.97B
– –
-654,099
Closed -$22.3M
DYN icon
92
Dyne Therapeutics
DYN
$1.97B
– –
-672,096
Closed -$7.03M
IONS icon
93
Ionis Pharmaceuticals
IONS
$9.79B
– –
-357,915
Closed -$10.8M
IPSC icon
94
Century Therapeutics
IPSC
$42.3M
– –
-241,684
Closed -$115K
LPTX icon
95
Leap Therapeutics
LPTX
$12.6M
– –
-404,744
Closed -$123K
PRME icon
96
Prime Medicine
PRME
$611M
– –
-1,028,466
Closed -$2.05M
RGLS
97
DELISTED
Regulus Therapeutics
RGLS
– –
-2,694,044
Closed -$4.71M
TSVT
98
DELISTED
2seventy bio
TSVT
– –
-2,497,526
Closed -$12.3M
BCAX
99
Bicara Therapeutics Inc. Common Stock
BCAX
$655M
– –
-833,333
Closed -$10.9M
OPT
100
DELISTED
Opthea Limited American Depositary Shares
OPT
$0 ﹤0.01%
2,087,320
– –
1 2 3
4