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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

100 hedge funds and large institutions have $276M invested in Syros Pharmaceuticals, Inc. Common Stock in 2021 Q2 according to their latest regulatory filings, with 19 funds opening new positions, 48 increasing their positions, 20 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed

140% more repeat investments, than reductions

Existing positions increased: 48 | Existing positions reduced: 20

6% less funds holding

Funds holding: 106100 (-6)

24% less first-time investments, than exits

New positions opened: 19 | Existing positions closed: 25

42% less capital invested

Capital invested by funds: $475M → $276M (-$200M)

50% less funds holding in top 10

Funds holding in top 10: 21 (-1)

66% less call options, than puts

Call options by funds: $893K | Put options by funds: $2.66M

Holders
100
Holders Change
-6
Holders Change %
-5.66%
% of All Funds
1.74%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
19
Increased
48
Reduced
20
Closed
25
Calls
$893K
Puts
$2.66M
Net Calls
-$1.77M
Net Calls Change
+$81K
Name Holding Trade Value Shares
Change
Change in
Stake
AllianceBernstein
51
AllianceBernstein
Tennessee
$305K +$117K +1,980 +55%
Jane Street
52
Jane Street
New York
$289K +$90.2K +1,524 +40%
ACM
53
ACT Capital Management
Pennsylvania
$287K +$311K +5,250 New
Simplex Trading
54
Simplex Trading
Illinois
$247K +$132K +2,231 +97%
Jacobs Levy Equity Management
55
Jacobs Levy Equity Management
New Jersey
$232K -$122K -2,055 -33%
RG
56
Redmile Group
California
$212K -$1.03M -17,338 -82%
LPL Financial
57
LPL Financial
California
$208K +$111K +1,876 +97%
VEA
58
Virtus ETF Advisers
New York
$207K +$72.3K +1,221 +47%
Manulife (Manufacturers Life Insurance)
59
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$199K +$48.1K +812 +29%
Deutsche Bank
60
Deutsche Bank
Germany
$196K -$119K -2,003 -36%
New York State Common Retirement Fund
61
New York State Common Retirement Fund
New York
$185K +$2.43K +41 +1%
TI
62
Trexquant Investment
Connecticut
$184K +$98.5K +1,665 +98%
Bank of America
63
Bank of America
North Carolina
$180K -$49K -828 -20%
HW
64
Hancock Whitney
Mississippi
$152K +$98.2K +1,659 +147%
ProShare Advisors
65
ProShare Advisors
Maryland
$142K +$29.2K +493 +23%
XT
66
XTX Topco
Cayman Islands
$142K +$87.9K +1,485 +133%
TRCT
67
Tower Research Capital (TRC)
New York
$136K -$55.9K -945 -27%
State Board of Administration of Florida Retirement System
68
State Board of Administration of Florida Retirement System
Florida
$129K +$13K +219 +10%
Group One Trading
69
Group One Trading
Illinois
$127K +$138K +2,335 New
VOYA Investment Management
70
VOYA Investment Management
Georgia
$124K +$15.1K +255 +13%
Russell Investments Group
71
Russell Investments Group
United Kingdom
$109K -$142K -2,407 -54%
PPA
72
Parametric Portfolio Associates
Washington
$104K +$113K +1,911 New
Invesco
73
Invesco
Georgia
$99K +$41.6K +703 +63%
RJA
74
Raymond James & Associates
Florida
$84K +$91.7K +1,550 New
Principal Financial Group
75
Principal Financial Group
Iowa
$78K +$24.7K +417 +41%

SYRS Hedge Fund Activity: Q2 2021 in Review

100 of the 5,746 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q2 2021, worth a combined $276M — down 42% from $475M a quarter earlier.

Sellers outnumbered buyers: 25 funds closed out of SYRS and 19 opened new positions — a net loss of 6 holders — while 20 trimmed existing stakes and 48 added.

The largest buyer was Altium Capital Management, adding an estimated $5.62M. The largest seller was ARK Investment Management, exiting entirely with an estimated $57.7M sold.

  • 100 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q2 2021, down from 106 in Q1 2021.
  • Funds reported $276M of Syros Pharmaceuticals, Inc. Common Stock stock for Q2 2021, down 42% quarter-over-quarter.
  • 19 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q2 2021 and 25 closed out, a net change of -6 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q2 2021 was Altium Capital Management, an estimated $5.62M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q2 2021 was ARK Investment Management, an estimated $57.7M sold.

Based on aggregated 13F filings for Q2 2021.