SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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100 hedge funds and large institutions have $276M invested in Syros Pharmaceuticals, Inc. Common Stock in 2021 Q2 according to their latest regulatory filings, with 19 funds opening new positions, 48 increasing their positions, 20 reducing their positions, and 25 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
100
Holders Change
-6
Holders Change %
-5.66%
% of All Funds
1.75%
Holding in Top 10
1
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-50%
% of All Funds
0.02%
New
19
Increased
48
Reduced
20
Closed
25
Calls
$893K
Puts
$2.66M
Net Calls
-$1.77M
Net Calls Change
+$81K

Top Buyers

1
ACM
1
Altium Capital Management
New York
$5.87M
2
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$4.65M
3
SCM
3
Sio Capital Management
New York
$4.36M
4
OFM
4
Omega Fund Management
Massachusetts
$12.4M
5
AG
5
Artal Group
Luxembourg
$9.27M

Top Sellers

1
AIM
1
ARK Investment Management
Florida
$0
2
Sumitomo Mitsui Trust Group
2
Sumitomo Mitsui Trust Group
Japan
$0
3
NAMA
3
Nikko Asset Management Americas
New York
$0
4
BBA
4
Baker Bros. Advisors
New York
$357K
5
Citadel Advisors
5
Citadel Advisors
Florida
$443K
Name Holding Trade Value Shares
Change 		Shares
Change %
Marshall Wace
26
Marshall Wace
United Kingdom
$1.62M +$1.62M +29,641 New
Los Angeles Capital Management
27
Los Angeles Capital Management
California
$1.48M +$987K +18,113 +200%
CSS
28
Cubist Systematic Strategies
Connecticut
$1.41M +$1.26M +23,197 +891%
Two Sigma Advisers
29
Two Sigma Advisers
New York
$1.4M -$216K -3,970 -13%
Bank of New York Mellon
30
Bank of New York Mellon
New York
$1.02M +$215K +3,949 +27%
JPMorgan Chase & Co
31
JPMorgan Chase & Co
New York
$1M -$2.62M -48,036 -72%
Nuveen Asset Management
32
Nuveen Asset Management
Illinois
$984K +$185K +3,390 +23%
Susquehanna International Group
33
Susquehanna International Group
Pennsylvania
$798K +$305K +5,607 +62%
GCP
34
GSA Capital Partners
United Kingdom
$768K +$415K +7,616 +117%
Two Sigma Investments
35
Two Sigma Investments
New York
$656K -$491K -9,003 -43%
PP
36
PDT Partners
New York
$637K -$167K -3,064 -21%
Assenagon Asset Management
37
Assenagon Asset Management
Luxembourg
$631K +$631K +11,579 New
Ensign Peak Advisors
38
Ensign Peak Advisors
Utah
$545K – – –
EGM
39
Engineers Gate Manager
New York
$448K +$448K +8,220 New
AA
40
ALPS Advisors
Colorado
$444K -$164K -3,004 -27%
Citadel Advisors
41
Citadel Advisors
Florida
$443K -$3.36M -61,703 -88%
PAI
42
Palo Alto Investors
California
$439K – – –
California State Teachers Retirement System (CalSTRS)
43
California State Teachers Retirement System (CalSTRS)
California
$433K +$45.2K +830 +12%
Qube Research & Technologies (QRT)
44
Qube Research & Technologies (QRT)
United Kingdom
$429K +$230K +4,228 +116%
Connor, Clark & Lunn Investment Management (CC&L)
45
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$414K +$414K +7,605 New
BBA
46
Baker Bros. Advisors
New York
$357K -$3.4M -62,467 -91%
RhumbLine Advisers
47
RhumbLine Advisers
Massachusetts
$353K +$98.3K +1,802 +39%
QI
48
QS Investors
New York
$349K – – –
State of Wisconsin Investment Board
49
State of Wisconsin Investment Board
Wisconsin
$326K -$129K -2,370 -28%
Barclays
50
Barclays
United Kingdom
$320K -$99.6K -1,828 -24%
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