BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+30.37%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$12B
AUM Growth
+$12B
Cap. Flow
-$219M
Cap. Flow %
-1.82%
Top 10 Hldgs %
76.74%
Holding
140
New
18
Increased
23
Reduced
51
Closed
10

Top Buys

1
NVTA
Invitae Corporation
NVTA
$110M
2
ONCE
Spark Therapeutics, Inc. Common Stock
ONCE
$103M
3
GEVA
SYNAGEVA BIOPHARMA CORP COM STK (DE)
GEVA
$97.5M
4
BMRN icon
BioMarin Pharmaceuticals
BMRN
$60.6M
5
SGEN
Seagen Inc. Common Stock
SGEN
$35.9M

Top Sells

1
AVNR
AVANIR PHARMACEUTICALS, INC CL A
AVNR
$653M
2
SLXP
SALIX PHARMACEUTICALS LTD DEL
SLXP
$73M
3
VNDA icon
Vanda Pharmaceuticals
VNDA
$25.3M
4
PCYC
PHARMACYCLICS INC
PCYC
$22.9M
5
XOMA icon
Xoma
XOMA
$8.06M

Sector Composition

1 Healthcare 40.26%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
OSUR icon
101
OraSure Technologies
OSUR
$239M
$1.5M 0.01%
229,397
-5,267
-2% -$34.4K
ALDX icon
102
Aldeyra Therapeutics
ALDX
$352M
$1.45M 0.01%
+142,000
New +$1.45M
RIGL icon
103
Rigel Pharmaceuticals
RIGL
$699M
$1.28M 0.01%
357,187
-124,785
-26% -$445K
LOXO
104
DELISTED
Loxo Oncology, Inc
LOXO
$1.25M 0.01%
100,000
– –
ALNY icon
105
Alnylam Pharmaceuticals
ALNY
$59.1B
$1.18M 0.01%
11,340
-260
-2% -$27.1K
XLRN
106
DELISTED
Acceleron Pharma Inc.
XLRN
$1.1M 0.01%
28,765
– –
AKAO
107
DELISTED
Achaogen, Inc.
AKAO
$976K 0.01%
100,000
– –
MDGL icon
108
Madrigal Pharmaceuticals
MDGL
$9.56B
$949K 0.01%
489,053
-10,947
-2% -$21.2K
NBSE
109
DELISTED
NeuBase Therapeutics, Inc. Common Stock
NBSE
$941K 0.01%
+370,370
New +$941K
QURE icon
110
uniQure
QURE
$933M
$730K 0.01%
30,000
-672
-2% -$16.4K
FPRX
111
DELISTED
Five Prime Therapeutics, Inc.
FPRX
$440K ﹤0.01%
19,247
-576
-3% -$13.2K
AEGR
112
DELISTED
Aegerion Pharmaceuticals, Inc.
AEGR
$374K ﹤0.01%
+14,300
New +$374K
CCXI
113
DELISTED
ChemoCentryx, Inc.
CCXI
$370K ﹤0.01%
49,064
-936
-2% -$7.06K
APTO
114
DELISTED
Aptose Biosciences, Inc.
APTO
$181K ﹤0.01%
33,397
-445,767
-93% -$2.42M
CYCCP icon
115
Cyclacel Pharmaceuticals, Inc. 6% Cnvrtbl. Prfrd. Stock
CYCCP
$86K ﹤0.01%
13,253
– –
BTX.WS
116
DELISTED
BioTime Inc Warrants (Expiring October 1, 2018)
BTX.WS
$40K ﹤0.01%
20,084
-441
-2% -$878
ALBO
117
DELISTED
Albireo Pharma, Inc. Common Stock
ALBO
$36K ﹤0.01%
+30,179
New +$36K
AKTX
118
Akari Therapeutics
AKTX
$21.2M
– –
-673,887
Closed -$3.24M
FOLD icon
119
Amicus Therapeutics
FOLD
$2.43B
– –
-481,697
Closed -$4.01M
GERN icon
120
Geron
GERN
$912M
– –
-402,629
Closed -$1.31M
MNK
121
DELISTED
MALLINCKRODT PUBLIC LIMITED COMPANY
MNK
– –
-46,666
Closed -$4.62M
SGYP
122
DELISTED
Synergy Pharmaceuticals, Inc Common Stock
SGYP
– –
-973,245
Closed -$2.97M
TSRO
123
DELISTED
TESARO, Inc.
TSRO
– –
-31,218
Closed -$1.16M
QLTI
124
DELISTED
QLT Inc
QLTI
– –
-1,535,863
Closed -$6.16M
SLXP
125
DELISTED
SALIX PHARMACEUTICALS LTD DEL
SLXP
– –
-635,321
Closed -$73M
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5
6