Baker Bros. Advisors’s Acceleron Pharma Inc. XLRN Stock Holding History

Quarter	Market Value	Status	Shares	Shares Change %	Trade Value	Portfolio Weight	Portfolio Position
2021 Q4	–	Sell	-22,430	Closed	-$3.86M	–	126
2021 Q3	$3.86M	Hold	22,430	–	–	0.02%	104
2021 Q2	$2.82M	Hold	22,430	–	–	0.01%	107
2021 Q1	$3.04M	Hold	22,430	–	–	0.01%	108
2020 Q4	$2.87M	Sell	22,430 -3,210	-13%	-$411K	0.01%	106
2020 Q3	$2.89M	Sell	25,640 -1,360	-5%	-$153K	0.01%	93
2020 Q2	$2.57M	Hold	27,000	–	–	0.01%	95
2020 Q1	$2.43M	Buy	+27,000	New	+$2.43M	0.01%	85
2019 Q4	–	Sell	-83,900	Closed	-$3.32M	–	109
2019 Q3	$3.32M	Hold	83,900	–	–	0.02%	74
2019 Q2	$3.45M	Hold	83,900	–	–	0.02%	70
2019 Q1	$3.91M	Hold	83,900	–	–	0.03%	65
2018 Q4	$3.65M	Hold	83,900	–	–	0.03%	61
2018 Q3	$4.8M	Sell	83,900 -80,000	-49%	-$4.58M	0.03%	72
2018 Q2	$7.95M	Hold	163,900	–	–	0.06%	59
2018 Q1	$6.41M	Hold	163,900	–	–	0.05%	69
2017 Q4	$6.96M	Hold	163,900	–	–	0.06%	68
2017 Q3	$6.12M	Buy	163,900 +135,135	+470%	+$5.04M	0.05%	72
2017 Q2	$874K	Hold	28,765	–	–	0.01%	103
2017 Q1	$761K	Hold	28,765	–	–	0.01%	104
2016 Q4	$734K	Hold	28,765	–	–	0.01%	117
2016 Q3	$1.04M	Hold	28,765	–	–	0.01%	111
2016 Q2	$977K	Hold	28,765	–	–	0.01%	117
2016 Q1	$759K	Hold	28,765	–	–	0.01%	120
2015 Q4	$1.4M	Hold	28,765	–	–	0.01%	114
2015 Q3	$716K	Hold	28,765	–	–	0.01%	124
2015 Q2	$910K	Hold	28,765	–	–	0.01%	118
2015 Q1	$1.1M	Hold	28,765	–	–	0.01%	119
2014 Q4	$1.12M	Hold	28,765	–	–	0.01%	112
2014 Q3	$870K	Hold	28,765	–	–	0.01%	100
2014 Q2	$977K	Hold	28,765	–	–	0.01%	99
2014 Q1	$992K	Sell	28,765 -1,235	-4%	-$42.6K	0.01%	99
2013 Q4	$1.19M	Buy	+30,000	New	+$1.19M	0.02%	87