BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+4.11%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$14.7B
AUM Growth
+$14.7B
Cap. Flow
+$64.6M
Cap. Flow %
0.44%
Top 10 Hldgs %
85.95%
Holding
111
New
8
Increased
15
Reduced
6
Closed
2

Top Buys

1
NVTA
Invitae Corporation
NVTA
$94.2M
2
ACAD icon
Acadia Pharmaceuticals
ACAD
$56.2M
3
IGMS
IGM Biosciences
IGMS
$55.8M
4
ALLK
Allakos
ALLK
$26.7M
5
MYOK
MyoKardia, Inc. Common Stock
MYOK
$26.1M

Top Sells

1
ARRY
Array Biopharma Inc
ARRY
$132M
2
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
$94M
3
CPRX icon
Catalyst Pharmaceutical
CPRX
$6.46M
4
BCRX icon
BioCryst Pharmaceuticals
BCRX
$4.75M
5
INSM icon
Insmed
INSM
$4.1M

Sector Composition

1 Healthcare 93.55%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ASMB icon
51
Assembly Biosciences
ASMB
$183M
$7.9M 0.05%
803,246
– –
MRKR icon
52
Marker Therapeutics
MRKR
$11.2M
$7.67M 0.05%
1,500,000
– –
APLS icon
53
Apellis Pharmaceuticals
APLS
$3.51B
$7.56M 0.05%
313,725
– –
CPRX icon
54
Catalyst Pharmaceutical
CPRX
$2.42B
$7.13M 0.05%
1,341,902
-1,217,559
-48% -$6.46M
HOOK
55
DELISTED
HOOKIPA Pharma
HOOK
$6.7M 0.05%
892,857
– –
ACOR
56
DELISTED
Acorda Therapeutics, Inc.
ACOR
$6.41M 0.04%
2,232,589
+221,400
+11% +$635K
DERM
57
DELISTED
Dermira, Inc.
DERM
$5.8M 0.04%
906,943
– –
XBIT icon
58
XBiotech
XBIT
$90.9M
$5.45M 0.04%
521,327
+140,885
+37% +$1.47M
ALBO
59
DELISTED
Albireo Pharma, Inc. Common Stock
ALBO
$5M 0.03%
250,000
– –
ARAV
60
DELISTED
Aravive, Inc. Common Stock
ARAV
$4.98M 0.03%
664,088
+179,141
+37% +$1.34M
MIST icon
61
Milestone Pharmaceuticals
MIST
$151M
$4.97M 0.03%
266,667
– –
ORTX
62
DELISTED
Orchard Therapeutics plc American Depositary Shares
ORTX
$4.82M 0.03%
405,702
– –
HALO icon
63
Halozyme
HALO
$8.75B
$4.65M 0.03%
299,969
– –
NXTC icon
64
NextCure
NXTC
$13.3M
$4.63M 0.03%
150,000
– –
IFRX icon
65
InflaRx
IFRX
$117M
$4.39M 0.03%
+1,778,415
New +$4.39M
ANAB icon
66
AnaptysBio
ANAB
$630M
$3.96M 0.03%
113,086
– –
ACHN
67
DELISTED
Achillion Pharmaceuticals, Inc.
ACHN
$3.94M 0.03%
1,095,359
– –
GLPG icon
68
Galapagos
GLPG
$2.06B
$3.83M 0.03%
25,072
– –
BLUE
69
DELISTED
bluebird bio
BLUE
$3.67M 0.03%
40,000
– –
NGM
70
DELISTED
NGM Biopharmaceuticals, Inc. Common Stock
NGM
$3.46M 0.02%
250,000
– –
MIRM icon
71
Mirum Pharmaceuticals
MIRM
$3.75B
$3.35M 0.02%
+333,333
New +$3.35M
XLRN
72
DELISTED
Acceleron Pharma Inc.
XLRN
$3.32M 0.02%
83,900
– –
VYNE icon
73
VYNE Therapeutics
VYNE
$8.09M
$3.14M 0.02%
700,000
– –
HARP
74
DELISTED
Harpoon Therapeutics, Inc. Common Stock
HARP
$2.93M 0.02%
214,285
– –
VKTX icon
75
Viking Therapeutics
VKTX
$3.02B
$2.92M 0.02%
425,000
– –
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3
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