BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+16.15%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$11.4B
AUM Growth
+$11.4B
Cap. Flow
-$1.07B
Cap. Flow %
-9.36%
Top 10 Hldgs %
75.13%
Holding
140
New
10
Increased
24
Reduced
17
Closed
12

Top Buys

1
ALXN
Alexion Pharmaceuticals Inc
ALXN
$1.18B
2
ABBV icon
AbbVie
ABBV
$966M
3
SGEN
Seagen Inc. Common Stock
SGEN
$96.5M
4
DYAX
DYAX CORPORATION
DYAX
$50.5M
5
ATYR
aTyr Pharma
ATYR
$43.2M

Top Sells

1
PCYC
PHARMACYCLICS INC
PCYC
$2.31B
2
GEVA
SYNAGEVA BIOPHARMA CORP COM STK (DE)
GEVA
$1.14B
3
ANAC
ANACOR PHARMACEUTICALS INC COM
ANAC
$44.8M
4
VNDA icon
Vanda Pharmaceuticals
VNDA
$17M
5
BMRN icon
BioMarin Pharmaceuticals
BMRN
$14.4M

Sector Composition

1 Healthcare 72.37%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
ARCT icon
51
Arcturus Therapeutics
ARCT
$467M
$11.7M 0.1%
1,789,871
– –
MGNX icon
52
MacroGenics
MGNX
$121M
$11.6M 0.1%
305,043
– –
AGIO icon
53
Agios Pharmaceuticals
AGIO
$2.36B
$11.1M 0.1%
100,000
-49,954
-33% -$5.55M
LJPC
54
DELISTED
La Jolla Pharmaceutical Company
LJPC
$10.1M 0.09%
412,008
– –
LRMR icon
55
Larimar Therapeutics
LRMR
$337M
$9.96M 0.09%
287,677
+192,932
+204% +$6.68M
OSIR
56
DELISTED
Osiris Therapeutics, Inc. Common Stock
OSIR
$9.71M 0.09%
499,193
– –
VIRX
57
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$9.63M 0.08%
3,200,000
– –
RXDX
58
DELISTED
Ignyta, Inc.
RXDX
$8.62M 0.08%
571,000
– –
NGNE icon
59
Neurogene
NGNE
$284M
$8.31M 0.07%
1,197,366
+9,700
+0.8% +$67.3K
SAGE
60
DELISTED
Sage Therapeutics
SAGE
$7.67M 0.07%
105,000
+30,000
+40% +$2.19M
LGND icon
61
Ligand Pharmaceuticals
LGND
$3.25B
$7.41M 0.07%
73,386
– –
CNCE
62
DELISTED
Concert Pharmaceuticals, Inc.
CNCE
$7.38M 0.06%
495,908
– –
ARWR icon
63
Arrowhead Research
ARWR
$3.84B
$7.22M 0.06%
1,009,509
-280,678
-22% -$2.01M
KPTI icon
64
Karyopharm Therapeutics
KPTI
$61.4M
$5.9M 0.05%
216,990
– –
EPZM
65
DELISTED
Epizyme, Inc
EPZM
$5.58M 0.05%
232,481
– –
AMRN
66
Amarin Corp
AMRN
$311M
$5.43M 0.05%
2,205,710
– –
AFMD
67
DELISTED
Affimed
AFMD
$5.39M 0.05%
400,000
– –
CMRX
68
DELISTED
Chimerix, Inc.
CMRX
$5.32M 0.05%
115,216
– –
AERI
69
DELISTED
Aerie Pharmaceuticals, Inc.
AERI
$5.28M 0.05%
299,356
– –
VNDA icon
70
Vanda Pharmaceuticals
VNDA
$279M
$5.2M 0.05%
409,881
-1,340,349
-77% -$17M
MCRB icon
71
Seres Therapeutics
MCRB
$162M
$5.19M 0.05%
+125,000
New +$5.19M
ASMB icon
72
Assembly Biosciences
ASMB
$183M
$4.82M 0.04%
250,000
– –
RCPT
73
DELISTED
RECEPTOS INC COM STK (DE)
RCPT
$4.54M 0.04%
23,900
– –
JUNO
74
DELISTED
Juno Therapeutics, Inc.
JUNO
$4.27M 0.04%
80,000
-20,000
-20% -$1.07M
STML
75
DELISTED
Stemline Therapeutics, Inc.
STML
$3.93M 0.03%
333,497
– –
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3
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