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Baker Bros. Advisors’s Arrowhead Research ARWR Stock Holding History

Baker Bros. Advisors’s Portfolio ARWR Stock Details ARWR Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$125M Sell
1,992,783
-182,862
-8% -$11.6M 0.72% 21
2025
Q4 		$144M Buy
2,175,645
+504,883
+30% +$24.7M 0.85% 16
2025
Q3 		$57.6M Buy
1,670,762
+731,588
+78% +$16.1M 0.42% 25
2025
Q2 		$14.8M Buy
+939,174
New +$13.5M 0.14% 45
2018
Q4 		– Sell
-307,496
Closed -$5.89M – 94
2018
Q3 		$5.89M Buy
+307,496
New +$5.05M 0.04% 67
2016
Q4 		– Sell
-1,856,967
Closed -$13.6M – 134
2016
Q3 		$13.6M Buy
1,856,967
+847,458
+84% +$5.49M 0.12% 46
2016
Q2 		$5.37M Hold
1,009,509
– – 0.06% 70
2016
Q1 		$4.87M Hold
1,009,509
– – 0.05% 74
2015
Q4 		$6.21M Hold
1,009,509
– – 0.05% 71
2015
Q3 		$5.82M Hold
1,009,509
– – 0.05% 75
2015
Q2 		$7.22M Sell
1,009,509
-280,678
-22% -$1.93M 0.06% 71
2015
Q1 		$8.73M Buy
1,290,187
+59,385
+5% +$421K 0.07% 64
2014
Q4 		$9.08M Hold
1,230,802
– – 0.09% 50
2014
Q3 		$18.2M Sell
1,230,802
-200,000
-14% -$2.73M 0.23% 38
2014
Q2 		$20.5M Buy
1,430,802
+698,740
+95% +$9.16M 0.25% 36
2014
Q1 		$12M Sell
732,062
-2,357,938
-76% -$41.4M 0.15% 45
2013
Q4 		$33.5M Sell
3,090,000
-50,000
-2% -$400K 0.47% 28
2013
Q3 		$17.9M Buy
+3,140,000
New +$12.1M 0.25% 35

Other funds holding ARWR

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
FAM
Fred Alger Management New York $22.8B AUM 64.63% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
VPC
Vestal Point Capital New York $3.58B AUM 189.12% 1-Year Est. Return

Baker Bros. Advisors's ARWR Position: Q1 2026 in Review

Baker Bros. Advisors reduced its Arrowhead Research (ARWR) stake by 8.4% in Q1 2026, selling an estimated $11.6M and leaving 1,992,783 shares worth $125M. The position accounts for 0.72% of the portfolio, ranked #21.

Baker Bros. Advisors first reported a position in ARWR in Q3 2013 and has held it in 18 quarters since. The position peaked at $144M in Q4 2025. 436 funds tracked by Wall St. Rank hold ARWR as of Q1 2026.

  • Baker Bros. Advisors held 1,992,783 shares of Arrowhead Research worth $125M as of Q1 2026.
  • Baker Bros. Advisors sold 182,862 Arrowhead Research shares in Q1 2026, an estimated $11.6M.
  • Arrowhead Research made up 0.72% of Baker Bros. Advisors's portfolio in Q1 2026, its #21 holding.
  • Baker Bros. Advisors first reported a position in Arrowhead Research in Q3 2013 and has held it in 18 quarters since.
  • Baker Bros. Advisors's Arrowhead Research position peaked at $144M in Q4 2025.
  • 436 funds tracked by Wall St. Rank held Arrowhead Research as of Q1 2026.

Based on Baker Bros. Advisors's 13F filing for Q1 2026, filed 15 May 2026.