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Arrowhead Research

436 hedge funds and large institutions have $7.58B invested in Arrowhead Research in 2026 Q1 according to their latest regulatory filings, with 106 funds opening new positions, 169 increasing their positions, 113 reducing their positions, and 61 closing their positions.

New
Increased
Maintained
Reduced
Closed

90% more call options, than puts

Call options by funds: $106M | Put options by funds: $55.8M

74% more first-time investments, than exits

New positions opened: 106 | Existing positions closed: 61

50% more repeat investments, than reductions

Existing positions increased: 169 | Existing positions reduced: 113

38% more funds holding in top 10

Funds holding in top 10: 811 (+3)

9% more funds holding

Funds holding: 401436 (+35)

0.9% more ownership

Funds ownership: 85.43%86.34% (+0.9%)

2% less capital invested

Capital invested by funds: $7.71B → $7.58B (-$126M)

Holders
436
Holders Change
+35
Holders Change %
+8.73%
% of All Funds
5.37%
Holding in Top 10
11
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+37.5%
% of All Funds
0.14%
New
106
Increased
169
Reduced
113
Closed
61
Calls
$106M
Puts
$55.8M
Net Calls
+$50.4M
Net Calls Change
-$58.7M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$1.14B -$200M -3,157,063 -15%
ACA
2
Avoro Capital Advisors
New York
$671M +$4.75M +74,999 +0.7%
Fidelity Investments
3
Fidelity Investments
Massachusetts
$456M +$47.2M +746,244 +11%
VPM
4
Vanguard Portfolio Management
Pennsylvania
$448M +$452M +7,146,136 New
State Street
5
State Street
Massachusetts
$407M +$5.84M +92,300 +1%
VCM
6
Vanguard Capital Management
Pennsylvania
$378M +$382M +6,032,416 New
Geode Capital Management
7
Geode Capital Management
Massachusetts
$275M +$64.2M +1,013,865 +31%
FAM
8
Fred Alger Management
New York
$210M +$95.6M +1,509,496 +82%
Invesco
9
Invesco
Georgia
$206M +$173M +2,732,889 +499%
VPC
10
Vestal Point Capital
New York
$143M +$87M +1,375,000 +153%
BBA
11
Baker Bros. Advisors
New York
$125M -$11.6M -182,862 -8%
Goldman Sachs
12
Goldman Sachs
New York
$109M +$3.95M +62,401 +4%
Northern Trust
13
Northern Trust
Illinois
$104M +$19.6M +309,580 +23%
SL
14
Siren LLC
Connecticut
$101M +$7.28M +115,000 +8%
DM
15
Deerfield Management
New York
$98.6M -$16.4M -259,649 -14%
Janus Henderson Group
16
Janus Henderson Group
United Kingdom
$90.1M +$9.91M +156,544 +12%
UBS Group
17
UBS Group
Switzerland
$83.8M +$22.1M +348,984 +35%
UBS AM
18
UBS AM
Illinois
$83.5M +$4.47M +70,616 +6%
Pictet Asset Management
19
Pictet Asset Management
Switzerland
$79.6M +$15.5M +244,530 +24%
Charles Schwab
20
Charles Schwab
California
$74.7M -$10.2M -161,634 -12%
DCM
21
Driehaus Capital Management
Illinois
$74.6M -$36.7M -579,005 -33%
D.E. Shaw & Co
22
D.E. Shaw & Co
New York
$74.2M +$65.7M +1,037,774 +710%
Fisher Asset Management
23
Fisher Asset Management
Washington
$69.8M -$12.5M -198,159 -15%
Bank of America
24
Bank of America
North Carolina
$66.7M +$28M +442,426 +71%
HRCM
25
Hood River Capital Management
Florida
$66.2M +$66.9M +1,056,534 New