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Arrowhead Research

265 hedge funds and large institutions have $1.34B invested in Arrowhead Research in 2025 Q1 according to their latest regulatory filings, with 43 funds opening new positions, 89 increasing their positions, 82 reducing their positions, and 46 closing their positions.

New
Increased
Maintained
Reduced
Closed

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

9% more repeat investments, than reductions

Existing positions increased: 89 | Existing positions reduced: 82

7% less first-time investments, than exits

New positions opened: 43 | Existing positions closed: 46

1% less funds holding

Funds holding: 269265 (-4)

3.44% less ownership

Funds ownership: 80.16%76.72% (-3.4%)

25% less call options, than puts

Call options by funds: $4.66M | Put options by funds: $6.24M

28% less capital invested

Capital invested by funds: $1.88B → $1.34B (-$532M)

Holders
265
Holders Change
-4
Holders Change %
-1.49%
% of All Funds
3.55%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.07%
New
43
Increased
89
Reduced
82
Closed
46
Calls
$4.66M
Puts
$6.24M
Net Calls
-$1.58M
Net Calls Change
-$3.28M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$254M +$68.2M +3,748,154 +23%
Vanguard Group
2
Vanguard Group
Pennsylvania
$168M +$18.5M +1,018,273 +8%
ACA
3
Avoro Capital Advisors
New York
$142M
State Street
4
State Street
Massachusetts
$89.2M +$17.9M +983,022 +16%
SPC
5
Slate Path Capital
New York
$66.7M
UBS AM
6
UBS AM
Illinois
$61M +$50.5M +2,774,933 +138%
Fidelity Investments
7
Fidelity Investments
Massachusetts
$42.2M -$32.5M -1,786,001 -35%
Geode Capital Management
8
Geode Capital Management
Massachusetts
$37.6M -$84.3K -4,635 -0.2%
SL
9
Siren LLC
Connecticut
$34M -$4.21M -231,801 -8%
T. Rowe Price Investment Management
10
T. Rowe Price Investment Management
Maryland
$32.2M +$394K +21,686 +0.9%
Morgan Stanley
11
Morgan Stanley
New York
$23.6M +$5.68M +312,124 +20%
Norges Bank
12
Norges Bank
Norway
$23M -$4.58M -251,780 -12%
Goldman Sachs
13
Goldman Sachs
New York
$22.2M +$8.14M +447,456 +35%
UBS Group
14
UBS Group
Switzerland
$20.7M +$5.84M +321,234 +25%
Northern Trust
15
Northern Trust
Illinois
$15.4M -$4.98M -273,606 -18%
Aberdeen Group
16
Aberdeen Group
United Kingdom
$13.7M +$11.3M +622,752 +138%
Charles Schwab
17
Charles Schwab
California
$13.2M +$319K +17,570 +2%
Citadel Advisors
18
Citadel Advisors
Florida
$12.6M +$11.3M +618,953 +168%
Two Sigma Investments
19
Two Sigma Investments
New York
$10.6M +$742K +40,801 +5%
WFC
20
Western Financial Corp
California
$10.4M
Bank of America
21
Bank of America
North Carolina
$10.2M +$4.04M +222,226 +39%
Bank of New York Mellon
22
Bank of New York Mellon
New York
$9.89M -$982K -54,019 -7%
Two Sigma Advisers
23
Two Sigma Advisers
New York
$9.22M +$5.33M +293,100 +68%
Millennium Management
24
Millennium Management
New York
$8.8M -$4.07M -223,754 -24%
PFM
25
Privium Fund Management
Netherlands
$8.02M +$4.52M +248,628 +65%

ARWR Hedge Fund Activity: Q1 2025 in Review

265 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Arrowhead Research (ARWR) for Q1 2025, worth a combined $1.34B — down 28% from $1.88B a quarter earlier.

Sellers outnumbered buyers: 46 funds closed out of ARWR and 43 opened new positions — a net loss of 3 holders — while 82 trimmed existing stakes and 89 added.

The largest buyer was BlackRock, adding an estimated $68.2M. The largest seller was Fidelity Investments, cutting an estimated $32.5M.

  • 265 institutional investors held Arrowhead Research (ARWR) as of Q1 2025, down from 269 in Q4 2024.
  • Funds reported $1.34B of Arrowhead Research stock for Q1 2025, down 28% quarter-over-quarter.
  • 43 funds opened new Arrowhead Research positions in Q1 2025 and 46 closed out, a net change of -3 holders.
  • The largest Arrowhead Research buyer in Q1 2025 was BlackRock, an estimated $68.2M added.
  • The largest Arrowhead Research seller in Q1 2025 was Fidelity Investments, an estimated $32.5M sold.

Based on aggregated 13F filings for Q1 2025.