Arrowhead Research
ARWR
282 hedge funds and large institutions have $1.67B invested in Arrowhead Research in 2025 Q2 according to their latest regulatory filings, with 57 funds opening new positions, 98 increasing their positions, 81 reducing their positions, and 38 closing their positions.
50% more first-time investments, than exits
New positions opened: 57 | Existing positions closed: 38
25% more capital invested
Capital invested by funds: $1.34B → $1.67B (+$330M)
21% more repeat investments, than reductions
Existing positions increased: 98 | Existing positions reduced: 81
6% more funds holding
Funds holding: 265 → 282 (+17)
0.07% less ownership
Funds ownership: 76.72% → 76.65% (-0.07%)
22% less call options, than puts
Call options by funds: $8.24M | Put options by funds: $10.6M
40% less funds holding in top 10
Funds holding in top 10: 5 → 3 (-2)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Vanguard Group
Malvern,
Pennsylvania
|
+$33.3M |
| 2 |
Marshall Wace
London,
United Kingdom
|
+$30.1M |
| 3 |
Fidelity Investments
Boston,
Massachusetts
|
+$26.6M |
| 4 |
BBA
Baker Bros. Advisors
New York
|
+$13.5M |
| 5 |
TI
Trexquant Investment
Stamford,
Connecticut
|
+$7.23M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
UBS AM
Chicago,
Illinois
|
-$30.1M |
| 2 |
T. Rowe Price Investment Management
Baltimore,
Maryland
|
-$24.5M |
| 3 |
Citadel Advisors
Miami,
Florida
|
-$13.3M |
| 4 |
Two Sigma Investments
New York
|
-$10.1M |
| 5 |
State Street
Boston,
Massachusetts
|
-$9.01M |
ARWR Hedge Fund Activity: Q2 2025 in Review
282 of the 7,613 institutional investors tracked by Wall St. Rank reported a position in Arrowhead Research (ARWR) for Q2 2025, worth a combined $1.67B — up 25% from $1.34B a quarter earlier.
Buyers outnumbered sellers: 57 funds opened new ARWR positions and 38 closed out — a net gain of 19 holders — while 98 added to existing stakes and 81 trimmed.
The largest buyer was Vanguard Group, adding an estimated $33.3M. The largest seller was UBS AM, cutting an estimated $30.1M.
- 282 institutional investors held Arrowhead Research (ARWR) as of Q2 2025, up from 265 in Q1 2025.
- Funds reported $1.67B of Arrowhead Research stock for Q2 2025, up 25% quarter-over-quarter.
- 57 funds opened new Arrowhead Research positions in Q2 2025 and 38 closed out, a net change of +19 holders.
- The largest Arrowhead Research buyer in Q2 2025 was Vanguard Group, an estimated $33.3M added.
- The largest Arrowhead Research seller in Q2 2025 was UBS AM, an estimated $30.1M sold.
Based on aggregated 13F filings for Q2 2025.