BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+25.41%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$16.7B
AUM Growth
+$16.7B
Cap. Flow
-$346M
Cap. Flow %
-2.08%
Top 10 Hldgs %
86.98%
Holding
128
New
13
Increased
17
Reduced
8
Closed
15

Top Buys

1
SWTX
SpringWorks Therapeutics
SWTX
$39.8M
2
PRME icon
Prime Medicine
PRME
$19.1M
3
REPL icon
Replimune Group
REPL
$18.6M
4
SPRY icon
ARS Pharmaceuticals
SPRY
$17.1M
5
DNLI icon
Denali Therapeutics
DNLI
$13.9M

Top Sells

1
GBT
Global Blood Therapeutics, Inc.
GBT
$254M
2
CCXI
ChemoCentryx, Inc.
CCXI
$92.6M
3
TVTX icon
Travere Therapeutics
TVTX
$43.6M
4
FMTX
Forma Therapeutics Holdings, Inc. Common Stock
FMTX
$37.6M
5
ALT icon
Altimmune
ALT
$18.4M

Sector Composition

1 Healthcare 99.74%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
NRIX icon
26
Nurix Therapeutics
NRIX
$723M
$42.6M 0.26%
3,882,125
– –
KNSA icon
27
Kiniksa Pharmaceuticals
KNSA
$2.63B
$41.9M 0.25%
2,799,577
– –
SWTX
28
DELISTED
SpringWorks Therapeutics
SWTX
$39.8M 0.24%
+1,528,538
New +$39.8M
IDYA icon
29
IDEAYA Biosciences
IDYA
$2.26B
$30.3M 0.18%
1,668,355
– –
DNLI icon
30
Denali Therapeutics
DNLI
$2.24B
$30.3M 0.18%
1,088,738
+500,000
+85% +$13.9M
XENE icon
31
Xenon Pharmaceuticals
XENE
$2.99B
$29.6M 0.18%
751,639
– –
VERV
32
DELISTED
Verve Therapeutics
VERV
$27.4M 0.16%
1,416,530
– –
DICE
33
DELISTED
DICE Therapeutics, Inc. Common Stock
DICE
$26.9M 0.16%
862,207
+273,972
+47% +$8.55M
TVTX icon
34
Travere Therapeutics
TVTX
$1.75B
$25.8M 0.15%
1,225,255
-2,074,754
-63% -$43.6M
BCYC
35
Bicycle Therapeutics
BCYC
$492M
$25M 0.15%
843,814
– –
ANAB icon
36
AnaptysBio
ANAB
$630M
$24M 0.14%
775,924
+348,745
+82% +$10.8M
KRYS icon
37
Krystal Biotech
KRYS
$4.35B
$24M 0.14%
302,716
-119,469
-28% -$9.46M
DBVT
38
DBV Technologies
DBVT
$249M
$22.4M 0.13%
1,461,426
– –
FGEN icon
39
FibroGen
FGEN
$48.4M
$22M 0.13%
55,008
+22,379
+69% +$8.96M
RARE icon
40
Ultragenyx Pharmaceutical
RARE
$3.04B
$21.8M 0.13%
470,974
– –
HRTX icon
41
Heron Therapeutics
HRTX
$204M
$20.3M 0.12%
8,131,678
– –
TSVT
42
DELISTED
2seventy bio
TSVT
$19.3M 0.12%
2,062,744
– –
PRME icon
43
Prime Medicine
PRME
$595M
$19.1M 0.11%
+1,028,466
New +$19.1M
BMEA icon
44
Biomea Fusion
BMEA
$114M
$17.7M 0.11%
2,104,559
– –
BLUE
45
DELISTED
bluebird bio
BLUE
$17.3M 0.1%
124,986
– –
SPRY icon
46
ARS Pharmaceuticals
SPRY
$1.08B
$17.1M 0.1%
+2,006,451
New +$17.1M
NVTA
47
DELISTED
Invitae Corporation
NVTA
$15.6M 0.09%
8,402,035
– –
OPT
48
DELISTED
Opthea Limited American Depositary Shares
OPT
$14.4M 0.09%
2,691,391
– –
ADAP
49
Adaptimmune Therapeutics
ADAP
$13.9M
$14.4M 0.09%
9,830,877
– –
CBAY
50
DELISTED
Cymabay Therapeutics
CBAY
$13.6M 0.08%
2,170,464
– –
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