BBA

Baker Bros. Advisors Portfolio holdings

AUM $10.3B
This Quarter Return
+4.11%
1 Year Return
+63.34%
3 Year Return
+231.6%
5 Year Return
+293.68%
10 Year Return
+1,612.7%
AUM
$14.7B
AUM Growth
+$14.7B
Cap. Flow
+$64.6M
Cap. Flow %
0.44%
Top 10 Hldgs %
85.95%
Holding
111
New
8
Increased
15
Reduced
6
Closed
2

Top Buys

1
NVTA
Invitae Corporation
NVTA
$94.2M
2
ACAD icon
Acadia Pharmaceuticals
ACAD
$56.2M
3
IGMS
IGM Biosciences
IGMS
$55.8M
4
ALLK
Allakos
ALLK
$26.7M
5
MYOK
MyoKardia, Inc. Common Stock
MYOK
$26.1M

Top Sells

1
ARRY
Array Biopharma Inc
ARRY
$132M
2
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
$94M
3
CPRX icon
Catalyst Pharmaceutical
CPRX
$6.46M
4
BCRX icon
BioCryst Pharmaceuticals
BCRX
$4.75M
5
INSM icon
Insmed
INSM
$4.1M

Sector Composition

1 Healthcare 93.55%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
BCEL
26
DELISTED
Atreca, Inc. Class A Common Stock
BCEL
$43.2M 0.29%
3,532,760
– –
GWPH
27
DELISTED
GW Pharmaceuticals Plc American Depositary Shares
GWPH
$42.7M 0.29%
370,845
– –
ZYME icon
28
Zymeworks
ZYME
$1.07B
$42.4M 0.29%
1,708,472
– –
BOLD
29
DELISTED
Audentes Therapeutics, Inc
BOLD
$42.3M 0.29%
1,506,438
– –
INSM icon
30
Insmed
INSM
$30.3B
$39.3M 0.27%
2,229,760
-232,456
-9% -$4.1M
BCRX icon
31
BioCryst Pharmaceuticals
BCRX
$1.74B
$36.5M 0.25%
12,725,472
-1,657,201
-12% -$4.75M
ADPT icon
32
Adaptive Biotechnologies
ADPT
$1.96B
$36M 0.25%
1,165,411
– –
KRYS icon
33
Krystal Biotech
KRYS
$4.35B
$35.9M 0.24%
1,034,674
– –
NGNE icon
34
Neurogene
NGNE
$284M
$32.2M 0.22%
11,305,679
+371,525
+3% +$1.06M
CBAY
35
DELISTED
Cymabay Therapeutics
CBAY
$29.2M 0.2%
5,707,411
– –
ALLK
36
DELISTED
Allakos
ALLK
$26.7M 0.18%
+339,690
New +$26.7M
KNSA icon
37
Kiniksa Pharmaceuticals
KNSA
$2.63B
$23.8M 0.16%
2,799,577
– –
MRUS icon
38
Merus
MRUS
$5.04B
$20.7M 0.14%
1,160,014
– –
QURE icon
39
uniQure
QURE
$954M
$20.4M 0.14%
517,700
– –
URGN icon
40
UroGen Pharma
URGN
$896M
$17.8M 0.12%
+747,751
New +$17.8M
AXSM icon
41
Axsome Therapeutics
AXSM
$6.09B
$15.6M 0.11%
772,286
– –
XNCR icon
42
Xencor
XNCR
$594M
$14.4M 0.1%
428,120
– –
AIMT
43
DELISTED
Aimmune Therapeutics, Inc.
AIMT
$14.1M 0.1%
673,908
– –
PTGX icon
44
Protagonist Therapeutics
PTGX
$3.62B
$14.1M 0.1%
1,174,282
+179,200
+18% +$2.15M
LJPC
45
DELISTED
La Jolla Pharmaceutical Company
LJPC
$13.7M 0.09%
1,559,231
– –
ACGN
46
DELISTED
Aceragen, Inc. Common Stock
ACGN
$13.3M 0.09%
4,608,786
+2,964
+0.1% +$8.54K
SYRE icon
47
Spyre Therapeutics
SYRE
$1.02B
$13.2M 0.09%
1,713,604
– –
ALKS icon
48
Alkermes
ALKS
$4.95B
$12.2M 0.08%
625,030
+225,030
+56% +$4.39M
SYRS
49
DELISTED
Syros Pharmaceuticals, Inc. Common Stock
SYRS
$10.1M 0.07%
974,835
– –
SGMO icon
50
Sangamo Therapeutics
SGMO
$161M
$9.05M 0.06%
999,823
– –
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