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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

90 hedge funds and large institutions have $166M invested in Syros Pharmaceuticals, Inc. Common Stock in 2021 Q4 according to their latest regulatory filings, with 12 funds opening new positions, 31 increasing their positions, 31 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

0% more repeat investments, than reductions

Existing positions increased: 31 | Existing positions reduced: 31

10% less funds holding

Funds holding: 10090 (-10)

26% less capital invested

Capital invested by funds: $223M → $166M (-$57.1M)

45% less first-time investments, than exits

New positions opened: 12 | Existing positions closed: 22

66% less call options, than puts

Call options by funds: $85K | Put options by funds: $249K

Holders
90
Holders Change
-10
Holders Change %
-10%
% of All Funds
1.38%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
12
Increased
31
Reduced
31
Closed
22
Calls
$85K
Puts
$249K
Net Calls
-$164K
Net Calls Change
+$1.16M
Name Holding Trade Value Shares
Change
Change in
Stake
AIP
76
Ameritas Investment Partners
Nebraska
$12K
Osaic Holdings
77
Osaic Holdings
Arizona
$8K +$8.1K +200 +455%
ACM
78
Aquatic Capital Management
Illinois
$6K +$7.69K +190 New
CWM
79
CarsonAllaria Wealth Management
Illinois
$5K +$6.6K +163 New
QT
80
Quantbot Technologies
New York
$4K +$5.26K +130 New
SOW
81
State of Wyoming
Wyoming
$3K
Simplex Trading
82
Simplex Trading
Illinois
$1K -$181K -4,473 -99%
US Bancorp
83
US Bancorp
Minnesota
$1K -$1.01K -25 -38%
IA
84
IFP Advisors
Florida
$1K
Allspring Global Investments
85
Allspring Global Investments
North Carolina
$1K +$1.46K +36 New
APA
86
American Portfolios Advisors
New York
$844 +$1.05K +26 New
Manulife (Manufacturers Life Insurance)
87
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$117 +$6.24K +154 +4%
Marshall Wace
88
Marshall Wace
United Kingdom
-$820K -18,345 Closed
PP
89
PDT Partners
New York
-$429K -9,608 Closed
Assenagon Asset Management
90
Assenagon Asset Management
Luxembourg
-$389K -8,707 Closed
PAI
91
Palo Alto Investors
California
-$360K -8,060 Closed
AA
92
ALPS Advisors
Colorado
-$339K -7,590 Closed
State of Wisconsin Investment Board
93
State of Wisconsin Investment Board
Wisconsin
-$267K -5,975 Closed
RG
94
Redmile Group
California
-$174K -3,891 Closed
VEA
95
Virtus ETF Advisers
New York
-$161K -3,609 Closed
SGI
96
Summit Global Investments
Utah
-$142K -3,180 Closed
ECM
97
ExodusPoint Capital Management
New York
-$137K -3,068 Closed
TI
98
Trexquant Investment
Connecticut
-$135K -3,016 Closed
MIM
99
MetLife Investment Management
New Jersey
-$97K -2,170 Closed
VF
100
Virtu Financial
New York
-$94K -2,094 Closed

SYRS Hedge Fund Activity: Q4 2021 in Review

90 of the 6,499 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q4 2021, worth a combined $166M — down 26% from $223M a quarter earlier.

Sellers outnumbered buyers: 22 funds closed out of SYRS and 12 opened new positions — a net loss of 10 holders — while 31 trimmed existing stakes and 31 added.

The largest buyer was Artal Group, adding an estimated $4.05M. The largest seller was Millennium Management, cutting an estimated $907K.

  • 90 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q4 2021, down from 100 in Q3 2021.
  • Funds reported $166M of Syros Pharmaceuticals, Inc. Common Stock stock for Q4 2021, down 26% quarter-over-quarter.
  • 12 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q4 2021 and 22 closed out, a net change of -10 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q4 2021 was Artal Group, an estimated $4.05M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q4 2021 was Millennium Management, an estimated $907K sold.

Based on aggregated 13F filings for Q4 2021.