SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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101 hedge funds and large institutions have $590M invested in Syros Pharmaceuticals, Inc. Common Stock in 2020 Q4 according to their latest regulatory filings, with 25 funds opening new positions, 36 increasing their positions, 29 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
101
Holders Change
+8
Holders Change %
+8.6%
% of All Funds
1.79%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.07%
New
25
Increased
36
Reduced
29
Closed
16
Calls
$1.7M
Puts
$1.3M
Net Calls
+$400K
Net Calls Change
+$413K

Top Buyers

1
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$62.8M
2
O
OrbiMed
New York
+$17M
3
OFM
Omega Fund Management
Massachusetts
+$17M
4
EC
EcoR1 Capital
California
+$10.9M
5
AG
Artal Group
Luxembourg
+$3.09M

Top Sellers

1
AIM
ARK Investment Management
Florida
-$23.6M
2
State Street
State Street
Massachusetts
-$10.6M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
-$5.82M
4
SCM
Sio Capital Management
New York
-$1.47M
5
PCM
Portolan Capital Management
Massachusetts
-$748K
Name Holding Trade Value Shares
Change 		Shares
Change %
MLICM
76
Metropolitan Life Insurance Company (MetLife)
New York
$136K – – –
SSA
77
Schonfeld Strategic Advisors
New York
$134K +$134K +1,230 New
Acadian Asset Management
78
Acadian Asset Management
Massachusetts
$126K +$75.3K +696 +148%
Thrivent Financial for Lutherans
79
Thrivent Financial for Lutherans
Minnesota
$122K +$122K +1,124 New
HS
80
HighVista Strategies
Massachusetts
$119K +$119K +1,100 New
Principal Financial Group
81
Principal Financial Group
Iowa
$114K +$114K +1,051 New
BC
82
Bridgefront Capital
Texas
$114K +$114K +1,054 New
BFM
83
Boothbay Fund Management
New York
$112K +$112K +1,030 New
CS
84
Credit Suisse
Switzerland
$109K -$164K -1,518 -60%
BNP Paribas Financial Markets
85
BNP Paribas Financial Markets
France
$98.3K -$12K -111 -11%
Bank of Montreal
86
Bank of Montreal
Ontario, Canada
$85K +$61.8K +515 +267%
AIP
87
Ameritas Investment Partners
Nebraska
$40K – – –
Simplex Trading
88
Simplex Trading
Illinois
$26K +$25K +232 +2,578%
Russell Investments Group
89
Russell Investments Group
United Kingdom
$22K -$174K -1,665 -89%
SB
90
Samsara BioCapital
California
$21.8K +$7.79K +78,125 +55%
PHK
91
Point72 Hong Kong
Hong Kong
$17K -$12.3K -114 -42%
Royal Bank of Canada
92
Royal Bank of Canada
Ontario, Canada
$14K -$111K -1,000 -89%
JCM
93
Jacobi Capital Management
Pennsylvania
$11K – – –
PCM
94
Penserra Capital Management
California
$11K +$6.91K +66 +169%
US Bancorp
95
US Bancorp
Minnesota
$8K +$3.62K +33 +83%
PAM
96
Panagora Asset Management
Massachusetts
$5K +$5K +43 New
Osaic Holdings
97
Osaic Holdings
Arizona
$1K -$5.5K -55 -85%
Daiwa Securities Group
98
Daiwa Securities Group
Japan
$1K -$1.7K -17 -63%
IA
99
IFP Advisors
Florida
$1K +$1K +11 New
AIG
100
American International Group
New York
$262 -$8 -70 -3%
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