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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

100 hedge funds and large institutions have $223M invested in Syros Pharmaceuticals, Inc. Common Stock in 2021 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 29 increasing their positions, 34 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed

7% more first-time investments, than exits

New positions opened: 16 | Existing positions closed: 15

0% more funds holding

Funds holding: 100100 (0)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

15% less repeat investments, than reductions

Existing positions increased: 29 | Existing positions reduced: 34

19% less capital invested

Capital invested by funds: $276M → $223M (-$52.9M)

86% less call options, than puts

Call options by funds: $224K | Put options by funds: $1.55M

Holders
100
Holders Change
Holders Change %
0%
% of All Funds
1.75%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.02%
New
16
Increased
29
Reduced
34
Closed
15
Calls
$224K
Puts
$1.55M
Net Calls
-$1.32M
Net Calls Change
+$446K
Name Holding Trade Value Shares
Change
Change in
Stake
LPL Financial
51
LPL Financial
California
$211K +$44.1K +903 +24%
Barclays
52
Barclays
United Kingdom
$200K -$67.9K -1,390 -24%
LCP
53
LGT Capital Partners
Switzerland
$194K +$212K +4,339 New
RG
54
Redmile Group
California
$174K
VEA
55
Virtus ETF Advisers
New York
$161K -$9.23K -189 -5%
Manulife (Manufacturers Life Insurance)
56
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$153K -$11.1K -228 -6%
New York State Common Retirement Fund
57
New York State Common Retirement Fund
New York
$153K +$1.32K +27 +0.8%
SGI
58
Summit Global Investments
Utah
$142K +$155K +3,180 New
AIG
59
American International Group
New York
$141K -$3.66K -75 -2%
California State Teachers Retirement System (CalSTRS)
60
California State Teachers Retirement System (CalSTRS)
California
$139K -$236K -4,839 -61%
Bank of America
61
Bank of America
North Carolina
$139K -$9.13K -187 -6%
SG Americas Securities
62
SG Americas Securities
New York
$139K +$152K +3,110 New
ECM
63
ExodusPoint Capital Management
New York
$137K +$150K +3,068 New
TI
64
Trexquant Investment
Connecticut
$135K -$17.2K -352 -10%
IC
65
IEQ Capital
California
$124K +$136K +2,780 New
JP Morgan Chase
66
JP Morgan Chase
New York
$120K -$766K -15,689 -85%
PPA
67
Parametric Portfolio Associates
Washington
$107K +$23.3K +478 +25%
VOYA Investment Management
68
VOYA Investment Management
Georgia
$101K
Invesco
69
Invesco
Georgia
$97K +$17.7K +363 +20%
MIM
70
MetLife Investment Management
New Jersey
$97K +$106K +2,170 New
VF
71
Virtu Financial
New York
$94K +$102K +2,094 New
ProShare Advisors
72
ProShare Advisors
Maryland
$92K -$26.6K -544 -21%
MLICM
73
Metropolitan Life Insurance Company (MetLife)
New York
$73.4K +$80.2K +1,642 New
OQS
74
Occudo Quantitative Strategies
Florida
$73K +$79.7K +1,632 New
DTL
75
Dynamic Technology Lab
Singapore
$57K -$1.76K -36 -3%

SYRS Hedge Fund Activity: Q3 2021 in Review

100 of the 5,713 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q3 2021, worth a combined $223M — down 19% from $276M a quarter earlier.

Buyers outnumbered sellers: 16 funds opened new SYRS positions and 15 closed out — a net gain of 1 holder — while 29 added to existing stakes and 34 trimmed.

The largest buyer was Adage Capital Partners, adding an estimated $4.63M. The largest seller was EcoR1 Capital, exiting entirely with an estimated $5.45M sold.

  • 100 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q3 2021, unchanged from Q2 2021.
  • Funds reported $223M of Syros Pharmaceuticals, Inc. Common Stock stock for Q3 2021, down 19% quarter-over-quarter.
  • 16 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q3 2021 and 15 closed out, a net change of +1 holder.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q3 2021 was Adage Capital Partners, an estimated $4.63M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q3 2021 was EcoR1 Capital, an estimated $5.45M sold.

Based on aggregated 13F filings for Q3 2021.