SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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106 hedge funds and large institutions have $475M invested in Syros Pharmaceuticals, Inc. Common Stock in 2021 Q1 according to their latest regulatory filings, with 17 funds opening new positions, 44 increasing their positions, 29 reducing their positions, and 12 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
106
Holders Change
+5
Holders Change %
+4.95%
% of All Funds
1.87%
Holding in Top 10
2
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-50%
% of All Funds
0.04%
New
17
Increased
44
Reduced
29
Closed
12
Calls
$1.32M
Puts
$3.17M
Net Calls
-$1.85M
Net Calls Change
-$2.25M

Top Buyers

1
Fidelity Investments
1
Fidelity Investments
Massachusetts
$67.4M
2
RCM
2
RA Capital Management
Massachusetts
$6.73M
3
BlackRock
3
BlackRock
New York
$31.2M
4
Sumitomo Mitsui Trust Group
4
Sumitomo Mitsui Trust Group
Japan
$38.6M
5
Vanguard Group
5
Vanguard Group
Pennsylvania
$20.4M

Top Sellers

1
AIM
1
ARK Investment Management
Florida
$57.7M
2
PCM
2
Portolan Capital Management
Massachusetts
$0
3
CIA
3
Capital Impact Advisors
Massachusetts
$0
4
Millennium Management
4
Millennium Management
New York
$1.26M
5
D.E. Shaw & Co
5
D.E. Shaw & Co
New York
$282K
Name Holding Trade Value Shares
Change 		Shares
Change %
Russell Investments Group
51
Russell Investments Group
United Kingdom
$331K +$315K +4,231 +2,015%
Bank of America
52
Bank of America
North Carolina
$309K +$203K +2,718 +193%
Jane Street
53
Jane Street
New York
$283K -$129K -1,723 -31%
D.E. Shaw & Co
54
D.E. Shaw & Co
New York
$282K -$1.47M -19,601 -84%
Qube Research & Technologies (QRT)
55
Qube Research & Technologies (QRT)
United Kingdom
$273K +$273K +3,649 New
AllianceBernstein
56
AllianceBernstein
Tennessee
$270K -$59.8K -800 -18%
TRCT
57
Tower Research Capital (TRC)
New York
$258K +$156K +2,087 +153%
VF
58
Virtu Financial
New York
$254K +$254K +3,399 New
New York State Common Retirement Fund
59
New York State Common Retirement Fund
New York
$251K +$33.6K +450 +15%
Manulife (Manufacturers Life Insurance)
60
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$212K +$17.4K +233 +9%
CSS
61
Cubist Systematic Strategies
Connecticut
$195K -$90.5K -1,208 -32%
VEA
62
Virtus ETF Advisers
New York
$193K +$3.37K +45 +2%
Simplex Trading
63
Simplex Trading
Illinois
$172K +$154K +2,064 +856%
JF
64
Jump Financial
Illinois
$163K +$163K +2,180 New
EMG
65
ETF Managers Group
New Jersey
$161K -$51.9K -718 -24%
State Board of Administration of Florida Retirement System
66
State Board of Administration of Florida Retirement System
Florida
$160K – – –
ProShare Advisors
67
ProShare Advisors
Maryland
$158K +$36.3K +485 +30%
VOYA Investment Management
68
VOYA Investment Management
Georgia
$151K +$7.35K +98 +5%
AQR Capital Management
69
AQR Capital Management
Connecticut
$147K -$54K -723 -27%
LPL Financial
70
LPL Financial
California
$145K +$39.8K +531 +38%
MIM
71
MetLife Investment Management
New Jersey
$134K +$4.19K +56 +3%
TI
72
Trexquant Investment
Connecticut
$127K -$19.2K -258 -13%
SG Americas Securities
73
SG Americas Securities
New York
$123K +$123K +1,651 New
AWE
74
Avidian Wealth Enterprises
Texas
$120K +$120K +1,600 New
PCM
75
Prelude Capital Management
New York
$109K +$2.99K +40 +3%
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