SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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101 hedge funds and large institutions have $590M invested in Syros Pharmaceuticals, Inc. Common Stock in 2020 Q4 according to their latest regulatory filings, with 25 funds opening new positions, 36 increasing their positions, 29 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
101
Holders Change
+8
Holders Change %
+8.6%
% of All Funds
1.79%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.07%
New
25
Increased
36
Reduced
29
Closed
16
Calls
$1.7M
Puts
$1.3M
Net Calls
+$400K
Net Calls Change
+$413K

Top Buyers

1
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$62.8M
2
O
OrbiMed
New York
+$17M
3
OFM
Omega Fund Management
Massachusetts
+$17M
4
EC
EcoR1 Capital
California
+$10.9M
5
AG
Artal Group
Luxembourg
+$3.09M

Top Sellers

1
AIM
ARK Investment Management
Florida
-$23.6M
2
State Street
State Street
Massachusetts
-$10.6M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
-$5.82M
4
SCM
Sio Capital Management
New York
-$1.47M
5
PCM
Portolan Capital Management
Massachusetts
-$748K
Name Holding Trade Value Shares
Change 		Shares
Change %
EMG
51
ETF Managers Group
New Jersey
$350K -$102K -858 -23%
Deutsche Bank
52
Deutsche Bank
Germany
$337K +$87K +802 +35%
Squarepoint
53
Squarepoint
New York
$320K +$188K +1,735 +143%
New York State Common Retirement Fund
54
New York State Common Retirement Fund
New York
$316K -$123K -1,130 -28%
AQR Capital Management
55
AQR Capital Management
Connecticut
$292K -$211K -1,943 -42%
Manulife (Manufacturers Life Insurance)
56
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$283K +$8.9K +82 +3%
VEA
57
Virtus ETF Advisers
New York
$275K -$103K -952 -27%
QI
58
QS Investors
New York
$267K +$267K +2,460 New
State Board of Administration of Florida Retirement System
59
State Board of Administration of Florida Retirement System
Florida
$232K – – –
ECM
60
ExodusPoint Capital Management
New York
$216K +$216K +1,989 New
TI
61
Trexquant Investment
Connecticut
$213K +$213K +1,961 New
VOYA Investment Management
62
VOYA Investment Management
Georgia
$208K +$47.6K +438 +30%
PPA
63
Parametric Portfolio Associates
Washington
$205K -$354K -3,264 -63%
Legal & General Group
64
Legal & General Group
United Kingdom
$189K +$133K +1,227 +239%
MIM
65
MetLife Investment Management
New Jersey
$188K – – –
ProShare Advisors
66
ProShare Advisors
Maryland
$176K +$41.2K +381 +31%
PCM
67
Prelude Capital Management
New York
$154K -$3.25K -30 -2%
Bank of America
68
Bank of America
North Carolina
$153K -$449K -4,138 -75%
LSAG
69
Lake Street Advisors Group
New Hampshire
$152K +$152K +1,400 New
LPL Financial
70
LPL Financial
California
$152K +$152K +1,402 New
Barclays
71
Barclays
United Kingdom
$150K -$58K -531 -28%
TRCT
72
Tower Research Capital (TRC)
New York
$148K -$74.2K -683 -33%
HW
73
Hancock Whitney
Mississippi
$145K – – –
Nisa Investment Advisors
74
Nisa Investment Advisors
Missouri
$141K +$141K +1,300 New
UBS Group
75
UBS Group
Switzerland
$140K +$72.7K +670 +108%
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