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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

75 hedge funds and large institutions have $112M invested in Syros Pharmaceuticals, Inc. Common Stock in 2024 Q1 according to their latest regulatory filings, with 22 funds opening new positions, 21 increasing their positions, 7 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

5,300% more call options, than puts

Call options by funds: $162K | Put options by funds: $3K

340% more first-time investments, than exits

New positions opened: 22 | Existing positions closed: 5

200% more repeat investments, than reductions

Existing positions increased: 21 | Existing positions reduced: 7

100% more funds holding in top 10

Funds holding in top 10: 12 (+1)

29% more funds holding

Funds holding: 5875 (+17)

24% less capital invested

Capital invested by funds: $147M → $112M (-$34.9M)

Holders
75
Holders Change
+17
Holders Change %
+29.31%
% of All Funds
1.08%
Holding in Top 10
2
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+100%
% of All Funds
0.03%
New
22
Increased
21
Reduced
7
Closed
5
Calls
$162K
Puts
$3K
Net Calls
+$159K
Net Calls Change
-$516K
Name Holding Trade Value Shares
Change
Change in
Stake
DCM
26
DAFNA Capital Management
California
$727K -$547K -79,035 -37%
Renaissance Technologies
27
Renaissance Technologies
New York
$641K +$423K +61,200 +104%
PA
28
Perceptive Advisors
New York
$625K +$807K +116,754 New
LPL Financial
29
LPL Financial
California
$407K -$37.3K -5,400 -7%
Two Sigma Investments
30
Two Sigma Investments
New York
$365K +$94.2K +13,629 +25%
State Street
31
State Street
Massachusetts
$313K +$62.2K +9,000 +18%
LCP
32
LGT Capital Partners
Switzerland
$294K
BCM
33
Bridgeway Capital Management
Texas
$276K +$83K +12,000 +30%
Man Group
34
Man Group
United Kingdom
$242K +$313K +45,294 New
Northern Trust
35
Northern Trust
Illinois
$197K -$21.2K -3,073 -8%
Bank of America
36
Bank of America
North Carolina
$181K +$164K +23,721 +237%
Citigroup
37
Citigroup
New York
$180K +$233K +33,624 New
Balyasny Asset Management
38
Balyasny Asset Management
Illinois
$124K +$160K +23,106 New
T. Rowe Price Associates
39
T. Rowe Price Associates
Maryland
$121K
1CM
40
1492 Capital Management
Wisconsin
$116K
HF
41
HRT Financial
New York
$104K +$135K +19,591 New
CGL
42
Clarius Group LLC
Washington
$99.6K
YIH
43
Y-Intercept (HK)
Hong Kong
$98.8K +$55K +7,951 +76%
Morgan Stanley
44
Morgan Stanley
New York
$93.4K +$98.3K +14,223 +439%
Acadian Asset Management
45
Acadian Asset Management
Massachusetts
$91K +$119K +17,162 New
BHCM
46
Brevan Howard Capital Management
Jersey
$85.8K +$111K +16,036 New
CIBC Asset Management
47
CIBC Asset Management
Ontario, Canada
$82.4K
HighTower Advisors
48
HighTower Advisors
Illinois
$80K -$602 -87 -0.6%
Squarepoint
49
Squarepoint
New York
$79.7K +$103K +14,890 New
American Century Companies
50
American Century Companies
Missouri
$72.9K +$94.2K +13,624 New

SYRS Hedge Fund Activity: Q1 2024 in Review

75 of the 6,943 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q1 2024, worth a combined $112M — down 24% from $147M a quarter earlier.

Buyers outnumbered sellers: 22 funds opened new SYRS positions and 5 closed out — a net gain of 17 holders — while 21 added to existing stakes and 7 trimmed.

The largest buyer was Opaleye Management, adding an estimated $2.96M. The largest seller was Blue Owl Capital Holdings, cutting an estimated $7.97M.

  • 75 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q1 2024, up from 58 in Q4 2023.
  • Funds reported $112M of Syros Pharmaceuticals, Inc. Common Stock stock for Q1 2024, down 24% quarter-over-quarter.
  • 22 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q1 2024 and 5 closed out, a net change of +17 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q1 2024 was Opaleye Management, an estimated $2.96M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q1 2024 was Blue Owl Capital Holdings, an estimated $7.97M sold.

Based on aggregated 13F filings for Q1 2024.