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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

58 hedge funds and large institutions have $147M invested in Syros Pharmaceuticals, Inc. Common Stock in 2023 Q4 according to their latest regulatory filings, with 16 funds opening new positions, 16 increasing their positions, 8 reducing their positions, and 5 closing their positions.

New
Increased
Maintained
Reduced
Closed

7,500% more call options, than puts

Call options by funds: $684K | Put options by funds: $9K

220% more first-time investments, than exits

New positions opened: 16 | Existing positions closed: 5

206% more capital invested

Capital invested by funds: $47.9M → $147M (+$98.9M)

100% more repeat investments, than reductions

Existing positions increased: 16 | Existing positions reduced: 8

21% more funds holding

Funds holding: 4858 (+10)

0% more funds holding in top 10

Funds holding in top 10: 11 (0)

Holders
58
Holders Change
+10
Holders Change %
+20.83%
% of All Funds
0.85%
Holding in Top 10
1
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.01%
New
16
Increased
16
Reduced
8
Closed
5
Calls
$684K
Puts
$9K
Net Calls
+$675K
Net Calls Change
-$364K
Name Holding Trade Value Shares
Change
Change in
Stake
State Street
26
State Street
Massachusetts
$385K +$55.8K +16,300 +49%
Northern Trust
27
Northern Trust
Illinois
$311K +$46.5K +13,576 +51%
BCM
28
Bridgeway Capital Management
Texas
$308K
6CM
29
683 Capital Management
New York
$284K +$125K +36,444 New
Assenagon Asset Management
30
Assenagon Asset Management
Luxembourg
$196K
Marshall Wace
31
Marshall Wace
United Kingdom
$193K +$85K +24,818 New
T. Rowe Price Associates
32
T. Rowe Price Associates
Maryland
$176K
1CM
33
1492 Capital Management
Wisconsin
$169K
Jane Street
34
Jane Street
New York
$165K +$72.4K +21,135 New
CGL
35
Clarius Group LLC
Washington
$145K
CIBC Asset Management
36
CIBC Asset Management
Ontario, Canada
$120K
HighTower Advisors
37
HighTower Advisors
Illinois
$117K
Corient Private Wealth
38
Corient Private Wealth
Florida
$93.5K -$50.2K -14,666 -55%
XT
39
XTX Topco
Cayman Islands
$85.7K +$37.7K +11,006 New
YIH
40
Y-Intercept (HK)
Hong Kong
$81.9K +$36K +10,512 New
Bank of America
41
Bank of America
North Carolina
$78.1K +$34.1K +9,953 +14,637%
IWC
42
Integrated Wealth Concepts
Massachusetts
$77.9K +$34.3K +10,000 New
Citadel Advisors
43
Citadel Advisors
Florida
$48.1K +$21.2K +6,180 New
EDRH
44
Edmond de Rothschild Holding
Switzerland
$34.1K
Morgan Stanley
45
Morgan Stanley
New York
$25.2K -$5K -1,460 -31%
Royal Bank of Canada
46
Royal Bank of Canada
Ontario, Canada
$23K +$7.05K +2,058 +218%
Group One Trading
47
Group One Trading
Illinois
$9.96K
PNC Financial Services Group
48
PNC Financial Services Group
Pennsylvania
$8.53K
Osaic Holdings
49
Osaic Holdings
Arizona
$8.44K +$2.7K +787 +266%
Russell Investments Group
50
Russell Investments Group
United Kingdom
$5.84K

SYRS Hedge Fund Activity: Q4 2023 in Review

58 of the 6,860 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q4 2023, worth a combined $147M — up 206% from $47.9M a quarter earlier.

Buyers outnumbered sellers: 16 funds opened new SYRS positions and 5 closed out — a net gain of 11 holders — while 16 added to existing stakes and 8 trimmed.

The largest buyer was Blue Owl Capital Holdings, opening a new position worth an estimated $5.11M. The largest seller was DAFNA Capital Management, cutting an estimated $175K.

  • 58 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q4 2023, up from 48 in Q3 2023.
  • Funds reported $147M of Syros Pharmaceuticals, Inc. Common Stock stock for Q4 2023, up 206% quarter-over-quarter.
  • 16 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q4 2023 and 5 closed out, a net change of +11 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q4 2023 was Blue Owl Capital Holdings, an estimated $5.11M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q4 2023 was DAFNA Capital Management, an estimated $175K sold.

Based on aggregated 13F filings for Q4 2023.