SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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94 hedge funds and large institutions have $53.1M invested in Syros Pharmaceuticals, Inc. Common Stock in 2022 Q1 according to their latest regulatory filings, with 15 funds opening new positions, 26 increasing their positions, 31 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
94
Holders Change
+4
Holders Change %
+4.44%
% of All Funds
1.49%
Holding in Top 10
–
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-100%
% of All Funds
–
New
15
Increased
26
Reduced
31
Closed
11
Calls
$33K
Puts
$14K
Net Calls
+$19K
Net Calls Change
+$183K

Top Buyers

1
Renaissance Technologies
1
Renaissance Technologies
New York
$975K
2
AG
2
Artal Group
Luxembourg
$4.17M
3
Millennium Management
3
Millennium Management
New York
$609K
4
Two Sigma Investments
4
Two Sigma Investments
New York
$222K
5
GCP
5
GSA Capital Partners
United Kingdom
$443K

Top Sellers

1
O
1
OrbiMed
New York
$0
2
Fidelity Investments
2
Fidelity Investments
Massachusetts
$6.58M
3
ACM
3
Altium Capital Management
New York
$0
4
RCM
4
RA Capital Management
Massachusetts
$0
5
Vanguard Group
5
Vanguard Group
Pennsylvania
$2.69M
Name Holding Trade Value Shares
Change 		Shares
Change %
BCM
26
Bridgeway Capital Management
Texas
$202K – – –
Nuveen Asset Management
27
Nuveen Asset Management
Illinois
$202K +$2.93K +266 +1%
Connor, Clark & Lunn Investment Management (CC&L)
28
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$163K +$22K +1,853 +16%
Charles Schwab
29
Charles Schwab
California
$152K -$18.8K -1,574 -11%
Citadel Advisors
30
Citadel Advisors
Florida
$152K +$76.8K +6,475 +102%
D.E. Shaw & Co
31
D.E. Shaw & Co
New York
$145K +$145K +12,181 New
LPL Financial
32
LPL Financial
California
$144K +$60.7K +5,108 +73%
Two Sigma Advisers
33
Two Sigma Advisers
New York
$127K +$19.2K +1,610 +18%
Jacobs Levy Equity Management
34
Jacobs Levy Equity Management
New Jersey
$106K -$17.3K -1,450 -14%
MFS
35
Mirabella Financial Services
United Kingdom
$102K +$102K +8,590 New
Marshall Wace
36
Marshall Wace
United Kingdom
$97K +$97K +8,189 New
Acadian Asset Management
37
Acadian Asset Management
Massachusetts
$97K +$97K +8,235 New
T. Rowe Price Associates
38
T. Rowe Price Associates
Maryland
$96K -$24.2K -2,040 -20%
Morgan Stanley
39
Morgan Stanley
New York
$95K +$12.7K +1,074 +15%
State Board of Administration of Florida Retirement System
40
State Board of Administration of Florida Retirement System
Florida
$93K – – –
RhumbLine Advisers
41
RhumbLine Advisers
Massachusetts
$76K -$3.32K -279 -4%
Franklin Resources
42
Franklin Resources
California
$75K – – –
Walleye Capital
43
Walleye Capital
New York
$67K +$53.9K +4,509 +410%
AllianceBernstein
44
AllianceBernstein
Tennessee
$63K +$239 +20 +0.4%
Ensign Peak Advisors
45
Ensign Peak Advisors
Utah
$54K – – –
XT
46
XTX Topco
Cayman Islands
$53K +$39.3K +3,304 +287%
VOYA Investment Management
47
VOYA Investment Management
Georgia
$47K +$17K +1,435 +57%
ACM
48
ACT Capital Management
Pennsylvania
$42K +$16.2K +1,350 +63%
New York State Common Retirement Fund
49
New York State Common Retirement Fund
New York
$41K +$168 +14 +0.4%
JPMorgan Chase & Co
50
JPMorgan Chase & Co
New York
$41K +$8.04K +677 +24%
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