SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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100 hedge funds and large institutions have $223M invested in Syros Pharmaceuticals, Inc. Common Stock in 2021 Q3 according to their latest regulatory filings, with 16 funds opening new positions, 29 increasing their positions, 34 reducing their positions, and 15 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
100
Holders Change
–
Holders Change %
0%
% of All Funds
1.76%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
16
Increased
29
Reduced
34
Closed
15
Calls
$224K
Puts
$1.55M
Net Calls
-$1.32M
Net Calls Change
+$446K

Top Buyers

1
Adage Capital Partners
1
Adage Capital Partners
Massachusetts
$8.05M
2
AG
2
Artal Group
Luxembourg
$8.94M
3
OFM
3
Omega Fund Management
Massachusetts
$11.2M
4
Vanguard Group
4
Vanguard Group
Pennsylvania
$13.3M
5
ACM
5
Altium Capital Management
New York
$5.69M

Top Sellers

1
EC
1
EcoR1 Capital
California
$0
2
Acadian Asset Management
2
Acadian Asset Management
Massachusetts
$0
3
Charles Schwab
3
Charles Schwab
California
$639K
4
Millennium Management
4
Millennium Management
New York
$1.41M
5
Morgan Stanley
5
Morgan Stanley
New York
$1.03M
Name Holding Trade Value Shares
Change 		Shares
Change %
Bank of New York Mellon
26
Bank of New York Mellon
New York
$876K +$41.5K +930 +5%
Marshall Wace
27
Marshall Wace
United Kingdom
$820K -$505K -11,296 -38%
Two Sigma Advisers
28
Two Sigma Advisers
New York
$772K -$373K -8,340 -33%
Charles Schwab
29
Charles Schwab
California
$639K -$1.11M -24,901 -64%
GCP
30
GSA Capital Partners
United Kingdom
$493K -$137K -3,065 -22%
Connor, Clark & Lunn Investment Management (CC&L)
31
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
$462K +$122K +2,726 +36%
Jacobs Levy Equity Management
32
Jacobs Levy Equity Management
New Jersey
$454K +$264K +5,909 +139%
Ensign Peak Advisors
33
Ensign Peak Advisors
Utah
$447K – – –
PP
34
PDT Partners
New York
$429K -$92.5K -2,072 -18%
Two Sigma Investments
35
Two Sigma Investments
New York
$408K -$130K -2,907 -24%
CSS
36
Cubist Systematic Strategies
Connecticut
$389K -$765K -17,101 -66%
Assenagon Asset Management
37
Assenagon Asset Management
Luxembourg
$389K -$128K -2,872 -25%
PAI
38
Palo Alto Investors
California
$360K – – –
Jane Street
39
Jane Street
New York
$352K +$114K +2,557 +48%
State Board of Administration of Florida Retirement System
40
State Board of Administration of Florida Retirement System
Florida
$351K +$246K +5,495 +233%
AA
41
ALPS Advisors
Colorado
$339K -$24.9K -557 -7%
Citadel Advisors
42
Citadel Advisors
Florida
$311K -$52.4K -1,172 -14%
RhumbLine Advisers
43
RhumbLine Advisers
Massachusetts
$298K +$9.15K +205 +3%
Franklin Resources
44
Franklin Resources
California
$286K +$286K +6,400 New
Deutsche Bank
45
Deutsche Bank
Germany
$268K +$106K +2,381 +66%
State of Wisconsin Investment Board
46
State of Wisconsin Investment Board
Wisconsin
$267K – – –
Simplex Trading
47
Simplex Trading
Illinois
$255K -$1.36K -24 -0.5%
AllianceBernstein
48
AllianceBernstein
Tennessee
$250K – – –
ACM
49
ACT Capital Management
Pennsylvania
$235K – – –
T. Rowe Price Associates
50
T. Rowe Price Associates
Maryland
$219K +$219K +4,908 New
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