SYRS

Syros Pharmaceuticals, Inc. Common Stock
SYRS

Overview Fund Activity
Delisted

SYRS was delisted on the 19th of March, 2025.

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101 hedge funds and large institutions have $590M invested in Syros Pharmaceuticals, Inc. Common Stock in 2020 Q4 according to their latest regulatory filings, with 25 funds opening new positions, 36 increasing their positions, 29 reducing their positions, and 16 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
101
Holders Change
+8
Holders Change %
+8.6%
% of All Funds
1.79%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.07%
New
25
Increased
36
Reduced
29
Closed
16
Calls
$1.7M
Puts
$1.3M
Net Calls
+$400K
Net Calls Change
+$413K

Top Buyers

1
BCLSI
Bain Capital Life Sciences Investors
Massachusetts
+$62.8M
2
O
OrbiMed
New York
+$17M
3
OFM
Omega Fund Management
Massachusetts
+$17M
4
EC
EcoR1 Capital
California
+$10.9M
5
AG
Artal Group
Luxembourg
+$3.09M

Top Sellers

1
AIM
ARK Investment Management
Florida
-$23.6M
2
State Street
State Street
Massachusetts
-$10.6M
3
Point72 Asset Management
Point72 Asset Management
Connecticut
-$5.82M
4
SCM
Sio Capital Management
New York
-$1.47M
5
PCM
Portolan Capital Management
Massachusetts
-$748K
Name Holding Trade Value Shares
Change 		Shares
Change %
CIA
26
Capital Impact Advisors
Massachusetts
$1.83M – – –
Nuveen Asset Management
27
Nuveen Asset Management
Illinois
$1.57M -$399K -3,675 -20%
Two Sigma Investments
28
Two Sigma Investments
New York
$1.51M -$157K -1,448 -9%
Bank of New York Mellon
29
Bank of New York Mellon
New York
$1.48M -$86.3K -795 -6%
Citigroup
30
Citigroup
New York
$1.4M +$1.33M +12,246 +1,872%
Jacobs Levy Equity Management
31
Jacobs Levy Equity Management
New Jersey
$1.33M +$667K +6,151 +101%
Goldman Sachs
32
Goldman Sachs
New York
$1.28M +$280K +2,581 +28%
Los Angeles Capital Management
33
Los Angeles Capital Management
California
$1.25M +$97.7K +901 +8%
Citadel Advisors
34
Citadel Advisors
Florida
$1.13M +$1.13M +10,428 New
IC
35
Ikarian Capital
Texas
$1.09M +$1.09M +10,000 New
Susquehanna International Group
36
Susquehanna International Group
Pennsylvania
$1.07M +$291K +2,684 +38%
California Public Employees Retirement System
37
California Public Employees Retirement System
California
$1.01M +$34.8K +321 +4%
State of Wisconsin Investment Board
38
State of Wisconsin Investment Board
Wisconsin
$974K -$89K -820 -8%
Renaissance Technologies
39
Renaissance Technologies
New York
$941K +$941K +8,670 New
PP
40
PDT Partners
New York
$917K +$37.2K +343 +4%
AA
41
ALPS Advisors
Colorado
$897K +$264K +2,435 +42%
Wells Fargo
42
Wells Fargo
California
$827K -$61.3K -565 -7%
Morgan Stanley
43
Morgan Stanley
New York
$822K +$739K +6,810 +886%
California State Teachers Retirement System (CalSTRS)
44
California State Teachers Retirement System (CalSTRS)
California
$682K – – –
Jane Street
45
Jane Street
New York
$597K +$597K +5,503 New
T. Rowe Price Associates
46
T. Rowe Price Associates
Maryland
$516K +$68.2K +629 +15%
RhumbLine Advisers
47
RhumbLine Advisers
Massachusetts
$515K +$28.1K +259 +6%
Marshall Wace
48
Marshall Wace
United Kingdom
$504K +$504K +4,642 New
AllianceBernstein
49
AllianceBernstein
Tennessee
$478K -$55.3K -510 -10%
CSS
50
Cubist Systematic Strategies
Connecticut
$414K +$321K +2,956 +346%
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