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SYRS

Syros Pharmaceuticals, Inc. Common Stock

Delisted

SYRS was delisted on the 19th of March, 2025.

62 hedge funds and large institutions have $446M invested in Syros Pharmaceuticals, Inc. Common Stock in 2019 Q3 according to their latest regulatory filings, with 5 funds opening new positions, 25 increasing their positions, 16 reducing their positions, and 11 closing their positions.

New
Increased
Maintained
Reduced
Closed

11,908% more call options, than puts

Call options by funds: $1.56M | Put options by funds: $13K

56% more repeat investments, than reductions

Existing positions increased: 25 | Existing positions reduced: 16

50% more funds holding in top 10

Funds holding in top 10: 23 (+1)

39% more capital invested

Capital invested by funds: $321M → $446M (+$125M)

9% less funds holding

Funds holding: 6862 (-6)

55% less first-time investments, than exits

New positions opened: 5 | Existing positions closed: 11

Holders
62
Holders Change
-6
Holders Change %
-8.82%
% of All Funds
1.36%
Holding in Top 10
3
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+50%
% of All Funds
0.07%
New
5
Increased
25
Reduced
16
Closed
11
Calls
$1.56M
Puts
$13K
Net Calls
+$1.55M
Net Calls Change
+$620K
Name Holding Trade Value Shares
Change
Change in
Stake
D.E. Shaw & Co
26
D.E. Shaw & Co
New York
$757K -$202K -2,139 -23%
Deutsche Bank
27
Deutsche Bank
Germany
$604K -$307K -3,249 -36%
California State Teachers Retirement System (CalSTRS)
28
California State Teachers Retirement System (CalSTRS)
California
$554K
State of Wisconsin Investment Board
29
State of Wisconsin Investment Board
Wisconsin
$540K +$159K +1,680 +48%
OAM
30
Oxford Asset Management
United Kingdom
$498K -$79.7K -844 -15%
RhumbLine Advisers
31
RhumbLine Advisers
Massachusetts
$404K -$2.55K -27 -0.7%
Goldman Sachs
32
Goldman Sachs
New York
$378K +$168K +1,776 +95%
New York State Common Retirement Fund
33
New York State Common Retirement Fund
New York
$366K
BCM
34
Bridgeway Capital Management
Texas
$346K
AllianceBernstein
35
AllianceBernstein
Tennessee
$302K +$79.3K +840 +41%
Wells Fargo
36
Wells Fargo
California
$287K -$19.1K -202 -7%
Manulife (Manufacturers Life Insurance)
37
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$236K -$9.82K -104 -4%
UBS Group
38
UBS Group
Switzerland
$235K +$159K +1,684 +290%
AIG
39
American International Group
New York
$227K -$1.42K -15 -0.7%
Millennium Management
40
Millennium Management
New York
$194K +$177K +1,878 New
MIM
41
MetLife Investment Management
New Jersey
$191K
Barclays
42
Barclays
United Kingdom
$185K -$42.1K -446 -20%
PP
43
PDT Partners
New York
$166K -$39.4K -417 -21%
Susquehanna International Group
44
Susquehanna International Group
Pennsylvania
$164K +$13.2K +140 +10%
ProShare Advisors
45
ProShare Advisors
Maryland
$160K +$3.59K +38 +3%
Bank of America
46
Bank of America
North Carolina
$142K +$53.7K +569 +71%
VOYA Investment Management
47
VOYA Investment Management
Georgia
$141K
MLICM
48
Metropolitan Life Insurance Company (MetLife)
New York
$138K +$98.1K +1,039 +358%
Morgan Stanley
49
Morgan Stanley
New York
$105K +$83.4K +883 +706%
WEC
50
Winslow Evans & Crocker
Massachusetts
$66K

SYRS Hedge Fund Activity: Q3 2019 in Review

62 of the 4,561 institutional investors tracked by Wall St. Rank reported a position in Syros Pharmaceuticals, Inc. Common Stock (SYRS) for Q3 2019, worth a combined $446M — up 39% from $321M a quarter earlier.

Sellers outnumbered buyers: 11 funds closed out of SYRS and 5 opened new positions — a net loss of 6 holders — while 16 trimmed existing stakes and 25 added.

The largest buyer was Arch Venture Management, opening a new position worth an estimated $36.4M. The largest seller was Alyeska Investment Group, exiting entirely with an estimated $3M sold.

  • 62 institutional investors held Syros Pharmaceuticals, Inc. Common Stock (SYRS) as of Q3 2019, down from 68 in Q2 2019.
  • Funds reported $446M of Syros Pharmaceuticals, Inc. Common Stock stock for Q3 2019, up 39% quarter-over-quarter.
  • 5 funds opened new Syros Pharmaceuticals, Inc. Common Stock positions in Q3 2019 and 11 closed out, a net change of -6 holders.
  • The largest Syros Pharmaceuticals, Inc. Common Stock buyer in Q3 2019 was Arch Venture Management, an estimated $36.4M added.
  • The largest Syros Pharmaceuticals, Inc. Common Stock seller in Q3 2019 was Alyeska Investment Group, an estimated $3M sold.

Based on aggregated 13F filings for Q3 2019.