|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$135M
|
+$1.37M
|
+56,561
|
+0.8%
|
|
|
2
|
EcoR1 Capital
San Francisco,
California
|
$129M
|
–
|
–
|
–
|
|
|
3
|
|
$126M
|
+$1.7M
|
+70,059
|
+1%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$78.7M
|
+$6.06M
|
+249,295
|
+6%
|
|
|
5
|
|
$66.3M
|
+$84M
|
+3,457,815
|
New
|
|
|
6
|
|
$63.9M
|
+$13.4M
|
+551,979
|
+20%
|
|
|
7
|
Citadel Advisors
Miami,
Florida
|
$58.9M
|
+$8.87M
|
+365,117
|
+13%
|
|
|
8
|
Bellevue Group
Kuesnacht,
Switzerland
|
$45.8M
|
+$72.9K
|
+3,000
|
+0.1%
|
|
|
9
|
T. Rowe Price Investment Management
Baltimore,
Maryland
|
$42.3M
|
+$53.7M
|
+2,208,234
|
New
|
|
|
10
|
UBS Group
Zurich,
Switzerland
|
$39.1M
|
+$38.1M
|
+1,566,881
|
+332%
|
|
|
11
|
|
$35.6M
|
-$11.5M
|
-472,225
|
-20%
|
|
|
12
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$34.1M
|
+$12.9M
|
+532,105
|
+43%
|
|
|
13
|
Opaleye Management
Boston,
Massachusetts
|
$33.6M
|
+$8.99M
|
+370,000
|
+29%
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$31.4M
|
-$162K
|
-6,677
|
-0.4%
|
|
|
15
|
New Leaf Venture Partners
New York
|
$30.4M
|
+$3.67M
|
+151,000
|
+11%
|
|
|
16
|
Fidelity Investments
Boston,
Massachusetts
|
$29.9M
|
-$32.2M
|
-1,324,777
|
-46%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$29M
|
-$202K
|
-8,320
|
-0.5%
|
|
|
18
|
Nextech Invest
Zurich,
Switzerland
|
$27M
|
–
|
–
|
–
|
|
|
19
|
Avidity Partners Management
Dallas,
Texas
|
$26M
|
-$3.38M
|
-139,000
|
-9%
|
|
|
20
|
|
$23.8M
|
-$1.93M
|
-79,565
|
-6%
|
|
|
21
|
Boxer Capital Management
San Diego,
California
|
$20.3M
|
+$25.7M
|
+1,058,614
|
New
|
|
|
22
|
|
$19.2M
|
+$11.6M
|
+477,588
|
+91%
|
|
|
23
|
Dimensional Fund Advisors
Austin,
Texas
|
$16.2M
|
+$4.53M
|
+186,254
|
+28%
|
|
|
24
|
Perceptive Advisors
New York
|
$14.2M
|
-$6.97M
|
-287,000
|
-28%
|
|
|
25
|
Finepoint Capital
Boston,
Massachusetts
|
$13.7M
|
+$3.39M
|
+139,400
|
+24%
|
|
