|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$106M
|
+$19M
|
+656,722
|
+17%
|
|
|
2
|
Canaan Partners IX
Menlo Park,
California
|
$94.2M
|
-$14.5M
|
-500,000
|
-11%
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$86.7M
|
–
|
–
|
–
|
|
|
4
|
|
$54.7M
|
+$3.08M
|
+106,228
|
+5%
|
|
|
5
|
New Leaf Venture Partners
New York
|
$53.9M
|
–
|
–
|
–
|
|
|
6
|
Bellevue Group
Kuesnacht,
Switzerland
|
$38.8M
|
+$1.73M
|
+59,800
|
+4%
|
|
|
7
|
Avidity Partners Management
Dallas,
Texas
|
$31.8M
|
+$7.87M
|
+271,400
|
+25%
|
|
|
8
|
Gilder Gagnon Howe & Co
New York
|
$31.3M
|
-$3.23M
|
-111,344
|
-8%
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$29.4M
|
+$4.31M
|
+148,715
|
+14%
|
|
|
10
|
|
$27.1M
|
+$22.1M
|
+762,484
|
+194%
|
|
|
11
|
5AM Venture Management
San Francisco,
California
|
$23.6M
|
–
|
–
|
–
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$19.8M
|
-$557K
|
-19,230
|
-2%
|
|
|
13
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$16.6M
|
+$6.8M
|
+234,512
|
+50%
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$15.7M
|
-$1.11M
|
-38,423
|
-5%
|
|
|
15
|
Deerfield Management
New York
|
$14.5M
|
-$11.4M
|
-394,500
|
-39%
|
|
|
16
|
Bank of America
Charlotte,
North Carolina
|
$11.6M
|
+$4.48M
|
+154,466
|
+46%
|
|
|
17
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$11.4M
|
–
|
–
|
–
|
|
|
18
|
Two Sigma Advisers
New York
|
$9.58M
|
+$1.55M
|
+53,400
|
+15%
|
|
|
19
|
|
$9.53M
|
+$5.18M
|
+178,784
|
+79%
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$9.25M
|
+$1.58M
|
+54,510
|
+16%
|
|
|
21
|
Citadel Advisors
Miami,
Florida
|
$8.82M
|
-$12.4M
|
-428,406
|
-53%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$7.85M
|
+$2.04M
|
+70,282
|
+27%
|
|
|
23
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$7.76M
|
-$425K
|
-14,664
|
-4%
|
|
|
24
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$7.58M
|
-$1.26M
|
-43,319
|
-12%
|
|
|
25
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$7.38M
|
-$9.06M
|
-312,500
|
-50%
|
|
