|
1
|
|
$122M
|
+$11M
|
+427,871
|
+10%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$112M
|
+$614K
|
+23,873
|
+0.5%
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$109M
|
-$33.9M
|
-1,316,403
|
-23%
|
|
|
4
|
EcoR1 Capital
San Francisco,
California
|
$99.7M
|
+$7.72M
|
+300,000
|
+8%
|
|
|
5
|
Avidity Partners Management
Dallas,
Texas
|
$68.8M
|
-$38.6M
|
-1,500,711
|
-35%
|
|
|
6
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$66.9M
|
+$4.64M
|
+180,318
|
+7%
|
|
|
7
|
Bellevue Group
Kuesnacht,
Switzerland
|
$52.8M
|
–
|
–
|
–
|
|
|
8
|
|
$49.6M
|
-$366K
|
-14,220
|
-0.7%
|
|
|
9
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$44.7M
|
+$5.99M
|
+232,886
|
+15%
|
|
|
10
|
New Leaf Venture Partners
New York
|
$32M
|
–
|
–
|
–
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$27.7M
|
+$253K
|
+9,849
|
+0.9%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$24.7M
|
+$1.01M
|
+39,173
|
+4%
|
|
|
13
|
Citadel Advisors
Miami,
Florida
|
$22.1M
|
-$5.07M
|
-197,137
|
-18%
|
|
|
14
|
American Century Companies
Kansas City,
Missouri
|
$21.3M
|
+$620K
|
+24,100
|
+3%
|
|
|
15
|
Aquilo Capital Management
San Francisco,
California
|
$15.5M
|
-$129K
|
-5,000
|
-0.8%
|
|
|
16
|
|
$15.2M
|
-$2.86M
|
-111,400
|
-15%
|
|
|
17
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$11.6M
|
-$705K
|
-27,394
|
-6%
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$11.5M
|
+$350K
|
+13,609
|
+3%
|
|
|
19
|
|
$11.2M
|
+$1.4M
|
+54,409
|
+14%
|
|
|
20
|
Brown Advisory
Baltimore,
Maryland
|
$10.9M
|
-$650K
|
-25,256
|
-5%
|
|
|
21
|
Finepoint Capital
Boston,
Massachusetts
|
$10.2M
|
-$2.08M
|
-80,800
|
-16%
|
|
|
22
|
Millennium Management
New York
|
$10.1M
|
+$4.17M
|
+162,275
|
+67%
|
|
|
23
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$10M
|
-$3.29M
|
-128,046
|
-24%
|
|
|
24
|
Gilder Gagnon Howe & Co
New York
|
$9.81M
|
+$399K
|
+15,514
|
+4%
|
|
|
25
|
UBS Group
Zurich,
Switzerland
|
$9.37M
|
-$567K
|
-22,043
|
-6%
|
|
