|
1
|
EcoR1 Capital
San Francisco,
California
|
$107M
|
+$35.6M
|
+1,449,275
|
+36%
|
|
|
2
|
|
$97.6M
|
+$1.62M
|
+66,139
|
+1%
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$95.6M
|
+$11.4M
|
+466,667
|
+11%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$90.5M
|
+$2.22M
|
+90,426
|
+2%
|
|
|
5
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$52.8M
|
-$132K
|
-5,365
|
-0.2%
|
|
|
6
|
Avidity Partners Management
Dallas,
Texas
|
$51.4M
|
-$3.88M
|
-158,229
|
-6%
|
|
|
7
|
Bellevue Group
Kuesnacht,
Switzerland
|
$41.7M
|
-$44.2K
|
-1,800
|
-0.1%
|
|
|
8
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$41M
|
+$6.99M
|
+285,008
|
+16%
|
|
|
9
|
|
$39.1M
|
-$220K
|
-8,976
|
-0.4%
|
|
|
10
|
New Leaf Venture Partners
New York
|
$25.4M
|
–
|
–
|
–
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$22.8M
|
+$1.05M
|
+42,606
|
+4%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$20.8M
|
+$1.53M
|
+62,416
|
+6%
|
|
|
13
|
Millennium Management
New York
|
$16.3M
|
+$10.4M
|
+421,970
|
+104%
|
|
|
14
|
American Century Companies
Kansas City,
Missouri
|
$16M
|
-$1.14M
|
-46,511
|
-5%
|
|
|
15
|
Citadel Advisors
Miami,
Florida
|
$12.3M
|
-$6.5M
|
-265,024
|
-30%
|
|
|
16
|
|
$9.93M
|
-$2.64M
|
-107,707
|
-18%
|
|
|
17
|
Finepoint Capital
Boston,
Massachusetts
|
$9.91M
|
+$2.29M
|
+93,200
|
+23%
|
|
|
18
|
Aquilo Capital Management
San Francisco,
California
|
$9.61M
|
-$3.31M
|
-134,788
|
-22%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$9.38M
|
+$366K
|
+14,914
|
+3%
|
|
|
20
|
Dimensional Fund Advisors
Austin,
Texas
|
$9.22M
|
+$6.3M
|
+256,689
|
+121%
|
|
|
21
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$8.79M
|
-$491K
|
-20,002
|
-4%
|
|
|
22
|
Brown Advisory
Baltimore,
Maryland
|
$8.56M
|
-$130K
|
-5,319
|
-1%
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$8.45M
|
+$1.63M
|
+66,430
|
+18%
|
|
|
24
|
Baker Bros. Advisors
New York
|
$8.12M
|
+$10.1M
|
+413,481
|
New
|
|
|
25
|
|
$7.94M
|
-$1.16M
|
-47,379
|
-10%
|
|
