|
1
|
|
$39.5M
|
–
|
–
|
–
|
|
|
2
|
New Leaf Venture Partners
New York
|
$33.7M
|
–
|
–
|
–
|
|
|
3
|
RA Capital Management
Boston,
Massachusetts
|
$31.6M
|
-$17.7M
|
-1,000,000
|
-32%
|
|
|
4
|
Deerfield Management
New York
|
$13.6M
|
–
|
–
|
–
|
|
|
5
|
|
$13.5M
|
+$16.3M
|
+916,514
|
New
|
|
|
6
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$9.22M
|
–
|
–
|
–
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$9.02M
|
–
|
–
|
–
|
|
|
8
|
|
$6.83M
|
-$1.47M
|
-82,742
|
-15%
|
|
|
9
|
Point72 Asset Management
Stamford,
Connecticut
|
$6.13M
|
+$7.36M
|
+415,000
|
New
|
|
|
10
|
Vanguard Group
Malvern,
Pennsylvania
|
$6.05M
|
+$1.1M
|
+61,993
|
+18%
|
|
|
11
|
Acuta Capital Partners
Redwood City,
California
|
$4.63M
|
+$5.57M
|
+314,000
|
New
|
|
|
12
|
Hillhouse Investment Management
Grand Cayman,
Cayman Islands
|
$3.4M
|
–
|
–
|
–
|
|
|
13
|
Sphera Funds Management
Tel Aviv,
Israel
|
$2.92M
|
-$1.29M
|
-73,000
|
-27%
|
|
|
14
|
Yale University
New Haven,
Connecticut
|
$2.73M
|
–
|
–
|
–
|
|
|
15
|
Ghost Tree Capital
New York
|
$2.58M
|
–
|
–
|
–
|
|
|
16
|
Redmile Group
San Francisco,
California
|
$2.23M
|
+$260K
|
+14,655
|
+11%
|
|
|
17
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$2.21M
|
–
|
–
|
–
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$1.86M
|
+$991K
|
+55,887
|
+80%
|
|
|
19
|
Marshall Wace North America
New York
|
$1.83M
|
+$2.19M
|
+123,732
|
New
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$1.72M
|
+$903K
|
+50,897
|
+77%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$1.38M
|
+$307K
|
+17,291
|
+23%
|
|
|
22
|
Citadel Advisors
Miami,
Florida
|
$748K
|
+$899K
|
+50,705
|
New
|
|
|
23
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$738K
|
–
|
–
|
–
|
|
|
24
|
EcoR1 Capital
San Francisco,
California
|
$738K
|
–
|
–
|
–
|
|
|
25
|
Charles Schwab
San Francisco,
California
|
$645K
|
+$15.8K
|
+893
|
+2%
|
|
