|
1
|
RA Capital Management
Boston,
Massachusetts
|
$40.3M
|
–
|
–
|
–
|
|
|
2
|
|
$34.4M
|
+$523K
|
+32,945
|
+1%
|
|
|
3
|
New Leaf Venture Partners
New York
|
$29.3M
|
–
|
–
|
–
|
|
|
4
|
Deerfield Management
New York
|
$11.8M
|
-$4.96M
|
-312,500
|
-25%
|
|
|
5
|
HHLR Advisors
Grand Cayman,
Cayman Islands
|
$8.03M
|
+$9.91M
|
+625,000
|
New
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$7.85M
|
–
|
–
|
–
|
|
|
7
|
|
$7.01M
|
+$4.52M
|
+284,656
|
+109%
|
|
|
8
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.47M
|
+$5.52M
|
+348,135
|
New
|
|
|
9
|
Sphera Funds Management
Tel Aviv,
Israel
|
$3.48M
|
+$493K
|
+31,053
|
+13%
|
|
|
10
|
Hillhouse Investment Management
Grand Cayman,
Cayman Islands
|
$2.96M
|
-$9.91M
|
-625,000
|
-73%
|
|
|
11
|
Vivo Capital
Palo Alto,
California
|
$2.69M
|
-$1.43M
|
-90,334
|
-30%
|
|
|
12
|
Yale University
New Haven,
Connecticut
|
$2.37M
|
–
|
–
|
–
|
|
|
13
|
Ghost Tree Capital
New York
|
$2.25M
|
–
|
–
|
–
|
|
|
14
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$1.93M
|
–
|
–
|
–
|
|
|
15
|
Redmile Group
San Francisco,
California
|
$1.75M
|
–
|
–
|
–
|
|
|
16
|
Millennium Management
New York
|
$1.04M
|
-$1.07M
|
-67,725
|
-46%
|
|
|
17
|
Northern Trust
Chicago,
Illinois
|
$982K
|
+$1.21M
|
+76,437
|
New
|
|
|
18
|
State Street
Boston,
Massachusetts
|
$903K
|
+$1.11M
|
+70,249
|
New
|
|
|
19
|
Pentwater Capital Management
Naples,
Florida
|
$896K
|
+$154K
|
+9,700
|
+16%
|
|
|
20
|
Geode Capital Management
Boston,
Massachusetts
|
$846K
|
+$1.04M
|
+65,837
|
New
|
|
|
21
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$643K
|
–
|
–
|
–
|
|
|
22
|
EcoR1 Capital
San Francisco,
California
|
$643K
|
–
|
–
|
–
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$550K
|
+$678K
|
+42,763
|
New
|
|
|
24
|
Matisse Capital
Portland,
Oregon
|
$535K
|
+$660K
|
+41,600
|
New
|
|
|
25
|
Birchview Capital
Burlington,
Vermont
|
$386K
|
–
|
–
|
–
|
|
