|
1
|
RA Capital Management
Boston,
Massachusetts
|
$52.9M
|
+$51.7M
|
+3,138,412
|
New
|
|
|
2
|
|
$44.6M
|
+$43.6M
|
+2,645,865
|
New
|
|
|
3
|
New Leaf Venture Partners
New York
|
$38.5M
|
+$37.6M
|
+2,283,048
|
New
|
|
|
4
|
Deerfield Management
New York
|
$20.8M
|
+$20.3M
|
+1,233,734
|
New
|
|
|
5
|
Hillhouse Investment Management
Grand Cayman,
Cayman Islands
|
$14.4M
|
+$14.1M
|
+855,308
|
New
|
|
|
6
|
Fidelity Investments
Boston,
Massachusetts
|
$10.3M
|
+$10.1M
|
+611,000
|
New
|
|
|
7
|
Vivo Capital
Palo Alto,
California
|
$5.06M
|
+$4.94M
|
+300,000
|
New
|
|
|
8
|
|
$4.4M
|
+$4.29M
|
+260,787
|
New
|
|
|
9
|
Sphera Funds Management
Tel Aviv,
Israel
|
$4.05M
|
+$3.95M
|
+240,000
|
New
|
|
|
10
|
Yale University
New Haven,
Connecticut
|
$3.11M
|
+$3.04M
|
+184,615
|
New
|
|
|
11
|
Ghost Tree Capital
New York
|
$2.95M
|
+$2.88M
|
+175,000
|
New
|
|
|
12
|
Laurion Capital Management
New York
|
$2.53M
|
+$2.47M
|
+150,000
|
New
|
|
|
13
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$2.53M
|
+$2.47M
|
+150,000
|
New
|
|
|
14
|
Millennium Management
New York
|
$2.51M
|
+$2.44M
|
+148,522
|
New
|
|
|
15
|
Redmile Group
San Francisco,
California
|
$2.3M
|
+$2.24M
|
+136,300
|
New
|
|
|
16
|
|
$2.23M
|
+$2.18M
|
+132,379
|
New
|
|
|
17
|
Perceptive Advisors
New York
|
$2.11M
|
+$2.06M
|
+125,000
|
New
|
|
|
18
|
|
$2.04M
|
+$1.99M
|
+121,067
|
New
|
|
|
19
|
Monashee Investment Management
Boston,
Massachusetts
|
$2.02M
|
–
|
–
|
–
|
|
|
20
|
Oxford Asset Management
Oxford,
United Kingdom
|
$1.46M
|
+$1.43M
|
+86,648
|
New
|
|
|
21
|
Pura Vida Investments
New York
|
$1.26M
|
+$1.23M
|
+75,000
|
New
|
|
|
22
|
Marshall Wace North America
New York
|
$1.09M
|
+$1.06M
|
+64,400
|
New
|
|
|
23
|
Pentwater Capital Management
Naples,
Florida
|
$1.01M
|
+$988K
|
+60,000
|
New
|
|
|
24
|
Wellington Management Group
Boston,
Massachusetts
|
$946K
|
+$923K
|
+56,075
|
New
|
|
|
25
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$844K
|
+$823K
|
+50,000
|
New
|
|
