|
1
|
Vanguard Group
Malvern,
Pennsylvania
|
$173M
|
+$8.73M
|
+334,179
|
+5%
|
|
|
2
|
EcoR1 Capital
San Francisco,
California
|
$166M
|
–
|
–
|
–
|
|
|
3
|
|
$160M
|
+$6.2M
|
+237,278
|
+4%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$94.9M
|
-$3.53M
|
-135,153
|
-3%
|
|
|
5
|
Fidelity Investments
Boston,
Massachusetts
|
$71M
|
+$5.34M
|
+204,317
|
+8%
|
|
|
6
|
|
$68.5M
|
-$4.85M
|
-185,568
|
-6%
|
|
|
7
|
Citadel Advisors
Miami,
Florida
|
$66.7M
|
+$1.78M
|
+68,052
|
+3%
|
|
|
8
|
Bellevue Group
Kuesnacht,
Switzerland
|
$58.8M
|
-$110K
|
-4,200
|
-0.2%
|
|
|
9
|
Paradigm Biocapital Advisors
New York
|
$57.6M
|
-$2.56M
|
-98,188
|
-4%
|
|
|
10
|
|
$57.4M
|
+$9.59M
|
+367,343
|
+19%
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$40.5M
|
-$1.46M
|
-55,961
|
-3%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$37.4M
|
-$585K
|
-22,403
|
-1%
|
|
|
13
|
Avidity Partners Management
Dallas,
Texas
|
$36.9M
|
-$38.9M
|
-1,490,845
|
-50%
|
|
|
14
|
New Leaf Venture Partners
New York
|
$35.3M
|
+$3.79M
|
+145,200
|
+11%
|
|
|
15
|
Nextech Invest
Zurich,
Switzerland
|
$34.7M
|
–
|
–
|
–
|
|
|
16
|
|
$32.6M
|
+$6.4M
|
+245,187
|
+23%
|
|
|
17
|
Braidwell
Stamford,
Connecticut
|
$31.6M
|
+$20M
|
+767,242
|
+148%
|
|
|
18
|
Opaleye Management
Boston,
Massachusetts
|
$30.9M
|
+$18.3M
|
+700,000
|
+126%
|
|
|
19
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$30.7M
|
+$463K
|
+17,723
|
+1%
|
|
|
20
|
Commodore Capital
New York
|
$29.6M
|
-$17.9M
|
-684,361
|
-36%
|
|
|
21
|
Perceptive Advisors
New York
|
$25.3M
|
–
|
–
|
–
|
|
|
22
|
|
$18.6M
|
+$4.17M
|
+159,701
|
+27%
|
|
|
23
|
Dimensional Fund Advisors
Austin,
Texas
|
$16.2M
|
+$5.05M
|
+193,241
|
+42%
|
|
|
24
|
Boxer Capital
San Diego,
California
|
$15M
|
–
|
–
|
–
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$14.5M
|
+$2.42M
|
+92,648
|
+19%
|
|
