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Opaleye Management’s Arvinas ARVN Stock Holding History

Opaleye Management’s Portfolio ARVN Stock Details ARVN Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-987,818
Closed -$8.42M – 56
2025
Q3 		$8.42M Sell
987,818
-692,182
-41% -$5.25M 1.19% 19
2025
Q2 		$12.4M Sell
1,680,000
-295,000
-15% -$2.17M 2.5% 10
2025
Q1 		$13.9M Buy
1,975,000
+350,000
+22% +$5.48M 3.09% 9
2024
Q4 		$33.6M Buy
1,625,000
+370,000
+29% +$8.99M 5.89% 6
2024
Q3 		$30.9M Buy
1,255,000
+700,000
+126% +$18.3M 5.16% 4
2024
Q2 		$14.8M Buy
555,000
+225,000
+68% +$7.17M 3.38% 6
2024
Q1 		$13.6M Buy
330,000
+66,300
+25% +$2.9M 2.97% 7
2023
Q4 		$10.9M Buy
+263,700
New +$6.16M 2.89% 11
2019
Q3 		– Sell
-220,000
Closed -$4.84M – 51
2019
Q2 		$4.84M Buy
+220,000
New +$4.62M 1.47% 28

Other funds holding ARVN

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Vanguard Group
Vanguard Group Malvern, Pennsylvania $6.9T AUM 27.45% 1-Year Est. Return
D.E. Shaw & Co
D.E. Shaw & Co New York $166B AUM 43.98% 1-Year Est. Return
P
Pfizer New York $239M AUM 232.47% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return
Point72 Asset Management
Point72 Asset Management Stamford, Connecticut $78.1B AUM 55.25% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
AC
Armistice Capital New York $5.62B AUM 36.06% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Qube Research & Technologies (QRT)
Qube Research & Technologies (QRT) London, United Kingdom $89.9B AUM 20.22% 1-Year Est. Return

Opaleye Management's ARVN Position: Q4 2025 in Review

Opaleye Management sold out of Arvinas (ARVN) in Q4 2025, closing a stake of 987,818 shares — an estimated $8.42M sold.

Opaleye Management first reported a position in ARVN in Q2 2019 and held it in 9 quarters. The position peaked at $33.6M in Q4 2024. 205 funds tracked by Wall St. Rank hold ARVN as of Q4 2025.

  • Opaleye Management reported no remaining Arvinas position as of Q4 2025 after selling out during the quarter.
  • Opaleye Management sold 987,818 Arvinas shares in Q4 2025, an estimated $8.42M.
  • Opaleye Management first reported a position in Arvinas in Q2 2019 and held it in 9 quarters.
  • Opaleye Management's Arvinas position peaked at $33.6M in Q4 2024.
  • 205 funds tracked by Wall St. Rank held Arvinas as of Q4 2025.

Based on Opaleye Management's 13F filing for Q4 2025, filed 17 Feb 2026.