|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$484M
|
+$16M
|
+234,155
|
+3%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$271M
|
+$2.14M
|
+31,372
|
+0.8%
|
|
|
3
|
|
$237M
|
+$1.33M
|
+19,519
|
+0.6%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$209M
|
+$13.4M
|
+196,104
|
+7%
|
|
|
5
|
Avidity Partners Management
Dallas,
Texas
|
$196M
|
+$26.4M
|
+387,327
|
+15%
|
|
|
6
|
Bellevue Group
Kuesnacht,
Switzerland
|
$147M
|
-$3.69M
|
-54,150
|
-2%
|
|
|
7
|
|
$127M
|
-$1.58M
|
-23,129
|
-1%
|
|
|
8
|
EcoR1 Capital
San Francisco,
California
|
$101M
|
+$93.6M
|
+1,373,629
|
+1,054%
|
|
|
9
|
Gilder Gagnon Howe & Co
New York
|
$91.5M
|
-$12M
|
-175,491
|
-11%
|
|
|
10
|
New Leaf Venture Partners
New York
|
$86.8M
|
–
|
–
|
–
|
|
|
11
|
State Street
Boston,
Massachusetts
|
$68.7M
|
+$4.6M
|
+67,431
|
+7%
|
|
|
12
|
Point72 Asset Management
Stamford,
Connecticut
|
$57.7M
|
+$14.8M
|
+216,531
|
+34%
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$55.5M
|
+$1.62M
|
+23,770
|
+3%
|
|
|
14
|
Wellington Management Group
Boston,
Massachusetts
|
$52.3M
|
+$9.77M
|
+143,274
|
+23%
|
|
|
15
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$49M
|
+$2.32M
|
+34,030
|
+5%
|
|
|
16
|
Aquilo Capital Management
San Francisco,
California
|
$46.8M
|
+$8.98M
|
+131,796
|
+23%
|
|
|
17
|
American Century Companies
Kansas City,
Missouri
|
$41.6M
|
+$7.77M
|
+114,020
|
+23%
|
|
|
18
|
|
$41.4M
|
+$4.83M
|
+70,801
|
+13%
|
|
|
19
|
|
$39.7M
|
-$1.79M
|
-26,201
|
-4%
|
|
|
20
|
Pictet Asset Management (Switzerland)
Geneva 73,
Switzerland
|
$37.3M
|
-$926K
|
-13,580
|
-2%
|
|
|
21
|
Paradigm Biocapital Advisors
New York
|
$33.1M
|
+$15.2M
|
+222,814
|
+83%
|
|
|
22
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$33M
|
-$2.15M
|
-31,599
|
-6%
|
|
|
23
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$30.8M
|
+$27.3K
|
+400
|
+0.1%
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$29.3M
|
-$1.04M
|
-15,195
|
-3%
|
|
|
25
|
UBS Group
Zurich,
Switzerland
|
$27.8M
|
+$8.62M
|
+126,540
|
+44%
|
|
