|
1
|
EcoR1 Capital
San Francisco,
California
|
$437M
|
–
|
–
|
–
|
|
|
2
|
|
$93.2M
|
-$2.85M
|
-53,050
|
-3%
|
|
|
3
|
Tang Capital Management
San Diego,
California
|
$73.8M
|
-$65K
|
-1,208
|
-0.1%
|
|
|
4
|
|
$55.1M
|
-$2.19M
|
-40,657
|
-4%
|
|
|
5
|
State Street
Boston,
Massachusetts
|
$55M
|
-$3.28M
|
-61,029
|
-6%
|
|
|
6
|
Affinity Asset Advisors
New York
|
$52.1M
|
+$26.6M
|
+495,308
|
+111%
|
|
|
7
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$47.3M
|
+$45.9M
|
+853,151
|
New
|
|
|
8
|
Palo Alto Investors
Palo Alto,
California
|
$35.4M
|
-$2.79M
|
-51,871
|
-8%
|
|
|
9
|
683 Capital Management
New York
|
$34.7M
|
-$1.24M
|
-23,093
|
-4%
|
|
|
10
|
|
$32.1M
|
-$4.9M
|
-90,992
|
-14%
|
|
|
11
|
First Light Asset Management
Edina,
Minnesota
|
$31.4M
|
-$4.35M
|
-80,807
|
-13%
|
|
|
12
|
|
$30.4M
|
–
|
–
|
–
|
|
|
13
|
Geode Capital Management
Boston,
Massachusetts
|
$28.9M
|
+$2.73M
|
+50,747
|
+11%
|
|
|
14
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$28.8M
|
+$28M
|
+519,870
|
New
|
|
|
15
|
Bank of America
Charlotte,
North Carolina
|
$27.8M
|
+$19.9M
|
+370,319
|
+283%
|
|
|
16
|
Arrowstreet Capital
Boston,
Massachusetts
|
$27.3M
|
-$3.64M
|
-67,624
|
-12%
|
|
|
17
|
Millennium Management
New York
|
$26.4M
|
-$18.2M
|
-337,999
|
-42%
|
|
|
18
|
Fidelity Investments
Boston,
Massachusetts
|
$26.2M
|
+$24M
|
+445,596
|
+1,644%
|
|
|
19
|
Two Sigma Investments
New York
|
$25.8M
|
+$11.2M
|
+208,448
|
+81%
|
|
|
20
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$20.2M
|
+$3.48M
|
+64,705
|
+22%
|
|
|
21
|
Woodline Partners
San Francisco,
California
|
$19.1M
|
-$8.43M
|
-156,767
|
-31%
|
|
|
22
|
|
$18.5M
|
-$3.56M
|
-66,171
|
-17%
|
|
|
23
|
Synergy Asset Management
Vancouver,
Washington
|
$17.6M
|
+$17.1M
|
+317,106
|
New
|
|
|
24
|
Nuveen
Charlotte,
North Carolina
|
$17.5M
|
-$33.4K
|
-620
|
-0.2%
|
|
|
25
|
|
$14.8M
|
+$5.76M
|
+106,972
|
+67%
|
|
