|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$296M
|
+$2.43M
|
+35,252
|
+0.9%
|
|
|
2
|
Janus Henderson Group
London,
|
$240M
|
-$7.55M
|
-109,353
|
-3%
|
|
|
3
|
Adage Capital Partners
Boston,
Massachusetts
|
$195M
|
+$26.1M
|
+378,784
|
+17%
|
|
|
4
|
Frazier Management
Seattle,
Washington
|
$169M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$140M
|
+$2.1M
|
+30,416
|
+2%
|
|
|
6
|
|
$132M
|
-$595K
|
-8,622
|
-0.5%
|
|
|
7
|
OppenheimerFunds
New York
|
$78.6M
|
+$253K
|
+3,671
|
+0.3%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$73M
|
-$8.48M
|
-122,888
|
-11%
|
|
|
9
|
Cormorant Asset Management
Boston,
Massachusetts
|
$67.2M
|
-$12.8M
|
-185,557
|
-17%
|
|
|
10
|
Capital World Investors
Los Angeles,
California
|
$63.4M
|
–
|
–
|
–
|
|
|
11
|
Viking Global Investors
Stamford,
Connecticut
|
$60.6M
|
+$5.81M
|
+84,123
|
+11%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$57.7M
|
+$25.2M
|
+364,593
|
+86%
|
|
|
13
|
Deerfield Management
New York
|
$54.3M
|
–
|
–
|
–
|
|
|
14
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$47.5M
|
+$2.42M
|
+35,000
|
+6%
|
|
|
15
|
Redmile Group
San Francisco,
California
|
$36.3M
|
+$9.17M
|
+132,868
|
+36%
|
|
|
16
|
Citadel Advisors
Miami,
Florida
|
$36.2M
|
+$1.62M
|
+23,502
|
+5%
|
|
|
17
|
Millennium Management
New York
|
$33.1M
|
+$13.4M
|
+194,340
|
+75%
|
|
|
18
|
Wells Fargo
San Francisco,
California
|
$20.5M
|
+$176K
|
+2,555
|
+0.9%
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$20.2M
|
+$1.55M
|
+22,520
|
+9%
|
|
|
20
|
Franklin Resources
San Mateo,
California
|
$20.1M
|
–
|
–
|
–
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$18.9M
|
+$130K
|
+1,879
|
+0.7%
|
|
|
22
|
BVF Inc
San Francisco,
California
|
$16.1M
|
–
|
–
|
–
|
|
|
23
|
Dimensional Fund Advisors
Austin,
Texas
|
$14M
|
+$7.76M
|
+112,442
|
+141%
|
|
|
24
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$12.4M
|
+$2.35M
|
+34,000
|
+25%
|
|
|
25
|
Capital International Investors
Los Angeles,
California
|
$11.8M
|
–
|
–
|
–
|
|
