|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$256M
|
+$5.75M
|
+77,268
|
+2%
|
|
|
2
|
Janus Henderson Group
London,
|
$216M
|
+$18.3M
|
+245,829
|
+8%
|
|
|
3
|
Frazier Management
Seattle,
Washington
|
$148M
|
–
|
–
|
–
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$146M
|
+$74M
|
+994,685
|
+76%
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$121M
|
+$2.77M
|
+37,271
|
+2%
|
|
|
6
|
|
$116M
|
+$14.1M
|
+189,685
|
+12%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$71.6M
|
+$1.13M
|
+15,185
|
+1%
|
|
|
8
|
Cormorant Asset Management
Boston,
Massachusetts
|
$70.5M
|
-$2.19M
|
-29,443
|
-3%
|
|
|
9
|
OppenheimerFunds
New York
|
$68.4M
|
-$1.81M
|
-24,325
|
-2%
|
|
|
10
|
Capital World Investors
Los Angeles,
California
|
$55.4M
|
+$6.25M
|
+84,000
|
+11%
|
|
|
11
|
Viking Global Investors
Stamford,
Connecticut
|
$47.6M
|
+$10.1M
|
+136,098
|
+22%
|
|
|
12
|
Deerfield Management
New York
|
$47.4M
|
+$7.14M
|
+95,973
|
+15%
|
|
|
13
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$39.2M
|
+$5.03M
|
+67,620
|
+12%
|
|
|
14
|
PFM Health Sciences
San Francisco,
California
|
$38.6M
|
-$33.4M
|
-449,016
|
-43%
|
|
|
15
|
Citadel Advisors
Miami,
Florida
|
$30.1M
|
-$13.2M
|
-176,895
|
-27%
|
|
|
16
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$27.1M
|
+$2.89M
|
+38,919
|
+10%
|
|
|
17
|
Redmile Group
San Francisco,
California
|
$23.2M
|
-$19.8M
|
-266,200
|
-42%
|
|
|
18
|
Wells Fargo
San Francisco,
California
|
$17.7M
|
-$1.62M
|
-21,725
|
-7%
|
|
|
19
|
Franklin Resources
San Mateo,
California
|
$17.6M
|
–
|
–
|
–
|
|
|
20
|
Millennium Management
New York
|
$16.5M
|
+$12.4M
|
+166,456
|
+181%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$16.4M
|
+$1.72M
|
+23,139
|
+10%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$16.2M
|
+$1.4M
|
+18,769
|
+8%
|
|
|
23
|
BVF Inc
San Francisco,
California
|
$14.1M
|
-$2.23M
|
-30,000
|
-12%
|
|
|
24
|
Capital International Investors
Los Angeles,
California
|
$10.3M
|
+$1.24M
|
+16,700
|
+12%
|
|
|
25
|
|
$9.92M
|
+$9.05M
|
+121,669
|
+359%
|
|
