|
1
|
EcoR1 Capital
San Francisco,
California
|
$42.9M
|
+$16.2M
|
+1,069,914
|
+54%
|
|
|
2
|
Vanguard Group
Malvern,
Pennsylvania
|
$33.2M
|
+$2.3M
|
+151,553
|
+7%
|
|
|
3
|
Frazier Management
Seattle,
Washington
|
$32.7M
|
–
|
–
|
–
|
|
|
4
|
Tang Capital Management
San Diego,
California
|
$32.4M
|
+$6.78M
|
+447,013
|
+24%
|
|
|
5
|
|
$28.7M
|
-$272K
|
-17,944
|
-0.9%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$27.6M
|
+$160K
|
+10,547
|
+0.5%
|
|
|
7
|
BVF Inc
San Francisco,
California
|
$23.9M
|
+$11.4M
|
+750,672
|
+80%
|
|
|
8
|
Aquilo Capital Management
San Francisco,
California
|
$20.3M
|
+$21.8M
|
+1,439,079
|
New
|
|
|
9
|
Boxer Capital
San Diego,
California
|
$18.4M
|
–
|
–
|
–
|
|
|
10
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$18M
|
-$16.8M
|
-1,104,533
|
-46%
|
|
|
11
|
Cormorant Asset Management
Boston,
Massachusetts
|
$15.7M
|
+$11.3M
|
+742,900
|
+204%
|
|
|
12
|
Dimensional Fund Advisors
Austin,
Texas
|
$7.73M
|
+$1.72M
|
+113,647
|
+26%
|
|
|
13
|
|
$7.45M
|
+$5.72M
|
+377,404
|
+252%
|
|
|
14
|
|
$7.12M
|
-$8.25M
|
-544,171
|
-52%
|
|
|
15
|
Perceptive Advisors
New York
|
$7.07M
|
-$7.58M
|
-500,000
|
-50%
|
|
|
16
|
|
$6.47M
|
+$1.41M
|
+92,670
|
+25%
|
|
|
17
|
Krensavage Asset Management
New York
|
$6.27M
|
+$52.6K
|
+3,468
|
+0.8%
|
|
|
18
|
Two Sigma Advisers
New York
|
$5.65M
|
+$2.09M
|
+138,100
|
+53%
|
|
|
19
|
Citadel Advisors
Miami,
Florida
|
$5.62M
|
+$5.67M
|
+373,717
|
+1,547%
|
|
|
20
|
|
$5.31M
|
–
|
–
|
–
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$5.05M
|
+$97K
|
+6,395
|
+2%
|
|
|
22
|
Burrage Capital Management
Boston,
Massachusetts
|
$4.48M
|
-$427K
|
-28,181
|
-8%
|
|
|
23
|
|
$4.4M
|
-$1.7M
|
-112,127
|
-26%
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$4.36M
|
-$33.9K
|
-2,237
|
-0.7%
|
|
|
25
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$4.24M
|
+$2.5M
|
+165,000
|
+122%
|
|
