|
1
|
EcoR1 Capital
San Francisco,
California
|
$532M
|
–
|
–
|
–
|
|
|
2
|
|
$124M
|
+$9.86M
|
+162,669
|
+10%
|
|
|
3
|
Tang Capital Management
San Diego,
California
|
$89.8M
|
–
|
–
|
–
|
|
|
4
|
State Street
Boston,
Massachusetts
|
$86.8M
|
+$17.8M
|
+293,749
|
+30%
|
|
|
5
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$61.2M
|
+$3.22M
|
+53,082
|
+6%
|
|
|
6
|
Affinity Asset Advisors
New York
|
$55.8M
|
-$6.9M
|
-113,891
|
-12%
|
|
|
7
|
|
$55.5M
|
–
|
–
|
–
|
|
|
8
|
Millennium Management
New York
|
$54.5M
|
+$20.1M
|
+331,744
|
+70%
|
|
|
9
|
Woodline Partners
San Francisco,
California
|
$48.4M
|
+$22.6M
|
+372,758
|
+108%
|
|
|
10
|
683 Capital Management
New York
|
$44.6M
|
+$2.12M
|
+35,000
|
+6%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$43.1M
|
+$7.13M
|
+117,632
|
+23%
|
|
|
12
|
Palo Alto Investors
Palo Alto,
California
|
$40.7M
|
-$2.1M
|
-34,672
|
-5%
|
|
|
13
|
|
$39.4M
|
+$15.2M
|
+251,327
|
+76%
|
|
|
14
|
First Light Asset Management
Edina,
Minnesota
|
$39.3M
|
+$1M
|
+16,573
|
+3%
|
|
|
15
|
|
$36.4M
|
-$2.4M
|
-39,630
|
-7%
|
|
|
16
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$35.6M
|
+$484K
|
+7,988
|
+2%
|
|
|
17
|
Apis Capital Advisors
New York
|
$33.5M
|
+$15.7M
|
+259,000
|
+109%
|
|
|
18
|
Sofinnova Investments
Menlo Park,
California
|
$33.3M
|
+$14.9M
|
+245,283
|
+99%
|
|
|
19
|
Arrowstreet Capital
Boston,
Massachusetts
|
$33M
|
-$210K
|
-3,469
|
-0.7%
|
|
|
20
|
Nuveen
Charlotte,
North Carolina
|
$28.4M
|
+$6.34M
|
+104,599
|
+33%
|
|
|
21
|
Bank of America
Charlotte,
North Carolina
|
$28.2M
|
-$5.05M
|
-83,274
|
-17%
|
|
|
22
|
Citadel Advisors
Miami,
Florida
|
$26.6M
|
+$9.75M
|
+160,923
|
+69%
|
|
|
23
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$26.4M
|
+$1.67M
|
+27,546
|
+8%
|
|
|
24
|
|
$21.9M
|
+$3.44M
|
+56,743
|
+21%
|
|
|
25
|
Two Sigma Investments
New York
|
$17.8M
|
-$12.2M
|
-202,088
|
-43%
|
|
