|
1
|
EcoR1 Capital
San Francisco,
California
|
$195M
|
+$8.85M
|
+369,400
|
+5%
|
|
|
2
|
Tang Capital Management
San Diego,
California
|
$68.2M
|
–
|
–
|
–
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$48.9M
|
-$10.5M
|
-440,118
|
-19%
|
|
|
4
|
|
$48M
|
-$5.85M
|
-244,234
|
-12%
|
|
|
5
|
Boxer Capital
San Diego,
California
|
$33.7M
|
–
|
–
|
–
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$33.2M
|
-$11.5M
|
-479,405
|
-27%
|
|
|
7
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$23.4M
|
-$5.49M
|
-228,861
|
-20%
|
|
|
8
|
Frazier Management
Seattle,
Washington
|
$23.3M
|
–
|
–
|
–
|
|
|
9
|
BVF Inc
San Francisco,
California
|
$21M
|
-$9.13M
|
-380,790
|
-32%
|
|
|
10
|
Dimensional Fund Advisors
Austin,
Texas
|
$20M
|
+$2.79M
|
+116,405
|
+18%
|
|
|
11
|
Woodline Partners
San Francisco,
California
|
$14M
|
+$2.67M
|
+111,205
|
+26%
|
|
|
12
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$13.9M
|
–
|
–
|
–
|
|
|
13
|
Palo Alto Investors
Palo Alto,
California
|
$11.3M
|
–
|
–
|
–
|
|
|
14
|
Baker Bros. Advisors
New York
|
$11.1M
|
–
|
–
|
–
|
|
|
15
|
Nuveen
Charlotte,
North Carolina
|
$10.6M
|
+$735K
|
+30,649
|
+8%
|
|
|
16
|
Great Point Partners
Greenwich,
Connecticut
|
$10.4M
|
+$9.59M
|
+400,051
|
New
|
|
|
17
|
Cormorant Asset Management
Boston,
Massachusetts
|
$9.98M
|
-$6.35M
|
-264,919
|
-41%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$9.96M
|
-$246K
|
-10,273
|
-3%
|
|
|
19
|
|
$8.16M
|
-$2.69M
|
-112,293
|
-26%
|
|
|
20
|
|
$7.95M
|
-$394K
|
-16,419
|
-5%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$7.75M
|
+$1.54M
|
+64,424
|
+27%
|
|
|
22
|
Two Sigma Advisers
New York
|
$6.97M
|
-$3.49M
|
-145,700
|
-35%
|
|
|
23
|
|
$6.71M
|
-$886K
|
-36,950
|
-13%
|
|
|
24
|
Renaissance Technologies
New York
|
$5.82M
|
-$155K
|
-6,482
|
-3%
|
|
|
25
|
Two Sigma Investments
New York
|
$5.41M
|
-$1.87M
|
-78,127
|
-27%
|
|
