|
1
|
EcoR1 Capital
San Francisco,
California
|
$68.7M
|
+$713K
|
+39,000
|
+1%
|
|
|
2
|
Tang Capital Management
San Diego,
California
|
$56.5M
|
+$4.35M
|
+237,851
|
+10%
|
|
|
3
|
Frazier Management
Seattle,
Washington
|
$51.7M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$50.4M
|
-$1.66M
|
-90,634
|
-4%
|
|
|
5
|
|
$46.6M
|
+$1.05M
|
+57,394
|
+3%
|
|
|
6
|
Aquilo Capital Management
San Francisco,
California
|
$35.5M
|
+$2.77M
|
+151,654
|
+11%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$32.1M
|
-$9.49M
|
-519,280
|
-27%
|
|
|
8
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$31.6M
|
+$2.59M
|
+141,543
|
+11%
|
|
|
9
|
Boxer Capital
San Diego,
California
|
$29M
|
–
|
–
|
–
|
|
|
10
|
BVF Inc
San Francisco,
California
|
$28.9M
|
-$7.24M
|
-395,836
|
-23%
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$21.6M
|
+$10.4M
|
+570,951
|
+143%
|
|
|
12
|
Cormorant Asset Management
Boston,
Massachusetts
|
$19.8M
|
-$4.06M
|
-222,062
|
-20%
|
|
|
13
|
|
$15.6M
|
+$4.42M
|
+241,706
|
+53%
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
$12.4M
|
+$135K
|
+7,367
|
+1%
|
|
|
15
|
|
$11.8M
|
–
|
–
|
–
|
|
|
16
|
Baker Bros. Advisors
New York
|
$11.5M
|
+$5.1M
|
+279,085
|
+119%
|
|
|
17
|
Two Sigma Advisers
New York
|
$9.13M
|
+$155K
|
+8,500
|
+2%
|
|
|
18
|
|
$8.39M
|
–
|
–
|
–
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$7.81M
|
-$145K
|
-7,937
|
-2%
|
|
|
20
|
|
$7.69M
|
+$4.35M
|
+237,809
|
+224%
|
|
|
21
|
Burrage Capital Management
Boston,
Massachusetts
|
$7.33M
|
-$69.6K
|
-3,805
|
-1%
|
|
|
22
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$6.85M
|
+$123K
|
+6,713
|
+2%
|
|
|
23
|
Two Sigma Investments
New York
|
$6.51M
|
+$124K
|
+6,801
|
+2%
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$6.47M
|
-$350K
|
-19,159
|
-6%
|
|
|
25
|
Fidelity Investments
Boston,
Massachusetts
|
$6.43M
|
+$1.66M
|
+90,838
|
+46%
|
|
