|
1
|
Frazier Management
Seattle,
Washington
|
$102M
|
+$85.9M
|
+3,688,448
|
New
|
|
|
2
|
Novo Holdings A/S
Hellerup,
Denmark
|
$84.2M
|
+$70.7M
|
+3,033,504
|
New
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$48.2M
|
+$40.5M
|
+1,738,600
|
New
|
|
|
4
|
Cormorant Asset Management
Boston,
Massachusetts
|
$24.9M
|
+$20.9M
|
+895,626
|
New
|
|
|
5
|
Perceptive Advisors
New York
|
$24.5M
|
+$20.5M
|
+881,957
|
New
|
|
|
6
|
Deerfield Management
New York
|
$23.5M
|
+$19.7M
|
+845,746
|
New
|
|
|
7
|
Franklin Resources
San Mateo,
California
|
$7.75M
|
+$6.5M
|
+279,200
|
New
|
|
|
8
|
Marshall Wace North America
New York
|
$6.92M
|
+$5.76M
|
+247,275
|
New
|
|
|
9
|
|
$6.89M
|
+$5.78M
|
+248,219
|
New
|
|
|
10
|
Adage Capital Partners
Boston,
Massachusetts
|
$6.8M
|
+$5.71M
|
+245,000
|
New
|
|
|
11
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$5.55M
|
+$4.66M
|
+200,000
|
New
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.67M
|
+$3.92M
|
+168,099
|
New
|
|
|
13
|
Baker Bros. Advisors
New York
|
$4.16M
|
+$3.49M
|
+150,000
|
New
|
|
|
14
|
Millennium Management
New York
|
$4.15M
|
+$3.48M
|
+149,506
|
New
|
|
|
15
|
Acuta Capital Partners
Redwood City,
California
|
$4.14M
|
+$3.86M
|
+165,690
|
New
|
|
|
16
|
|
$3.85M
|
+$3.23M
|
+138,738
|
New
|
|
|
17
|
International Biotechnology Trust
London,
United Kingdom
|
$2.79M
|
+$2.34M
|
+100,500
|
New
|
|
|
18
|
Graticule Asia Macro Advisors
New York
|
$2.59M
|
+$2.17M
|
+93,250
|
New
|
|
|
19
|
Geode Capital Management
Boston,
Massachusetts
|
$1.52M
|
+$1.28M
|
+54,865
|
New
|
|
|
20
|
Alyeska Investment Group
Chicago,
Illinois
|
$1.45M
|
+$1.22M
|
+52,250
|
New
|
|
|
21
|
Boxer Capital
San Diego,
California
|
$1.39M
|
+$1.16M
|
+50,000
|
New
|
|
|
22
|
Iguana Healthcare Management
New York
|
$1.39M
|
+$1.16M
|
+50,000
|
New
|
|
|
23
|
|
$1.24M
|
+$1.04M
|
+44,690
|
New
|
|
|
24
|
State Street
Boston,
Massachusetts
|
$995K
|
+$835K
|
+35,837
|
New
|
|
|
25
|
Spark Investment Management
New York
|
$962K
|
+$808K
|
+34,700
|
New
|
|
