|
1
|
EcoR1 Capital
San Francisco,
California
|
$47.5M
|
+$2.68M
|
+148,310
|
+5%
|
|
|
2
|
Tang Capital Management
San Diego,
California
|
$38.8M
|
+$1.8M
|
+100,000
|
+4%
|
|
|
3
|
Frazier Management
Seattle,
Washington
|
$34.2M
|
–
|
–
|
–
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$30.4M
|
-$3.45M
|
-191,503
|
-8%
|
|
|
5
|
|
$28.5M
|
-$2.84M
|
-157,644
|
-8%
|
|
|
6
|
Aquilo Capital Management
San Francisco,
California
|
$21.8M
|
-$2.04M
|
-113,081
|
-7%
|
|
|
7
|
Federated Hermes
Pittsburgh,
Pennsylvania
|
$20.7M
|
-$167K
|
-9,277
|
-0.7%
|
|
|
8
|
Boxer Capital
San Diego,
California
|
$19.2M
|
–
|
–
|
–
|
|
|
9
|
BVF Inc
San Francisco,
California
|
$18.1M
|
-$1.21M
|
-66,996
|
-5%
|
|
|
10
|
State Street
Boston,
Massachusetts
|
$17.6M
|
-$4.38M
|
-242,680
|
-17%
|
|
|
11
|
Citadel Advisors
Miami,
Florida
|
$14.1M
|
-$261K
|
-14,468
|
-1%
|
|
|
12
|
Cormorant Asset Management
Boston,
Massachusetts
|
$9.59M
|
-$4.25M
|
-235,838
|
-27%
|
|
|
13
|
|
$9.45M
|
-$1.06M
|
-58,821
|
-8%
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
$8.45M
|
+$327K
|
+18,139
|
+3%
|
|
|
15
|
|
$7.78M
|
–
|
–
|
–
|
|
|
16
|
Baker Bros. Advisors
New York
|
$7.19M
|
-$477K
|
-26,434
|
-5%
|
|
|
17
|
Geode Capital Management
Boston,
Massachusetts
|
$5.54M
|
+$471K
|
+26,107
|
+7%
|
|
|
18
|
Palo Alto Investors
Palo Alto,
California
|
$5.44M
|
+$6.65M
|
+368,722
|
New
|
|
|
19
|
Burrage Capital Management
Boston,
Massachusetts
|
$4.88M
|
+$43.9K
|
+2,435
|
+0.7%
|
|
|
20
|
Rock Springs Capital Management
Baltimore,
Maryland
|
$4.56M
|
+$43.3K
|
+2,400
|
+0.8%
|
|
|
21
|
Millennium Management
New York
|
$4.25M
|
+$3.09M
|
+171,437
|
+147%
|
|
|
22
|
Two Sigma Advisers
New York
|
$4.1M
|
-$2.36M
|
-130,600
|
-32%
|
|
|
23
|
Northern Trust
Chicago,
Illinois
|
$4.02M
|
-$314K
|
-17,402
|
-6%
|
|
|
24
|
Two Sigma Investments
New York
|
$3.96M
|
-$423K
|
-23,423
|
-8%
|
|
|
25
|
|
$3.89M
|
-$1.45M
|
-80,475
|
-23%
|
|
