Palo Alto Investors’s AnaptysBio ANAB Stock Holding History

Palo Alto Investors’s Portfolio ANAB Stock Details ANAB Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$40.7M	Sell	603,489 -34,672	-5%	-$2.1M	5.63%	5
2026 Q1	$35.4M	Sell	638,161 -51,871	-8%	-$2.79M	5.41%	6
2025 Q4	$33.5M	Buy	690,032 +16,512	+2%	+$644K	4.66%	6
2025 Q3	$20.6M	Sell	673,520 -139,301	-17%	-$3.2M	3.82%	8
2025 Q2	$18M	Sell	812,821 -207,892	-20%	-$4.35M	3.84%	9
2025 Q1	$19M	Buy	1,020,713 +176,742	+21%	+$2.95M	3.61%	10
2024 Q4	$11.2M	Hold	843,971	–	–	1.73%	15
2024 Q3	$28.3M	Buy	843,971 +40,330	+5%	+$1.38M	3.67%	11
2024 Q2	$20.1M	Buy	803,641 +3,735	+0.5%	+$87K	2.33%	11
2024 Q1	$18M	Buy	799,906 +113,024	+16%	+$2.68M	2.03%	14
2023 Q4	$14.7M	Buy	686,882 +255,658	+59%	+$4.41M	1.33%	18
2023 Q3	$7.74M	Hold	431,224	–	–	0.73%	16
2023 Q2	$8.77M	Hold	431,224	–	–	0.71%	18
2023 Q1	$9.38M	Buy	431,224 +200	+0%	+$4.86K	0.78%	17
2022 Q4	$13.4M	Hold	431,024	–	–	1.14%	15
2022 Q3	$11M	Hold	431,024	–	–	0.87%	17
2022 Q2	$8.75M	Hold	431,024	–	–	0.76%	20
2022 Q1	$10.7M	Sell	431,024 -5,568	-1%	-$169K	0.82%	19
2021 Q4	$15.2M	Hold	436,592	–	–	0.97%	19
2021 Q3	$11.8M	Hold	436,592	–	–	0.71%	23
2021 Q2	$11.3M	Hold	436,592	–	–	0.62%	24
2021 Q1	$9.41M	Buy	436,592 +20,300	+5%	+$512K	0.54%	22
2020 Q4	$8.95M	Buy	416,292 +47,570	+13%	+$1.16M	0.47%	21
2020 Q3	$5.44M	Buy	+368,722	New	+$6.65M	0.3%	24

Other funds holding ANAB

EcoR1 Capital San Francisco, California $2.06B AUM 215.32% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

TCM

Tang Capital Management San Diego, California $2.2B AUM 156.35% 1-Year Est. Return

State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

AAA

Affinity Asset Advisors New York $2.21B AUM 431.26% 1-Year Est. Return

Sanofi Paris, France $534M AUM 205.96% 1-Year Est. Return

Millennium Management New York $276B AUM 44.8% 1-Year Est. Return

Woodline Partners San Francisco, California $32.4B AUM 58.5% 1-Year Est. Return

6CM

683 Capital Management New York $2.04B AUM 94.26% 1-Year Est. Return

Palo Alto Investors's ANAB Position: Q2 2026 in Review

Palo Alto Investors reduced its AnaptysBio (ANAB) stake by 5.4% in Q2 2026, selling an estimated $2.1M and leaving 603,489 shares worth $40.7M. The position accounts for 5.63% of the portfolio, ranked #5.

Palo Alto Investors first reported a position in ANAB in Q3 2020 and has held it in 24 quarters since. 213 funds tracked by Wall St. Rank hold ANAB as of Q2 2026.

Palo Alto Investors held 603,489 shares of AnaptysBio worth $40.7M as of Q2 2026.
Palo Alto Investors sold 34,672 AnaptysBio shares in Q2 2026, an estimated $2.1M.
AnaptysBio made up 5.63% of Palo Alto Investors's portfolio in Q2 2026, its #5 holding.
Palo Alto Investors first reported a position in AnaptysBio in Q3 2020 and has held it in 24 quarters since.
213 funds tracked by Wall St. Rank held AnaptysBio as of Q2 2026.

Based on Palo Alto Investors's 13F filing for Q2 2026, filed 17 Aug 2026.