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AnaptysBio

147 hedge funds and large institutions have $816M invested in AnaptysBio in 2025 Q2 according to their latest regulatory filings, with 27 funds opening new positions, 45 increasing their positions, 55 reducing their positions, and 31 closing their positions.

New
Increased
Maintained
Reduced
Closed

83% more call options, than puts

Call options by funds: $5.28M | Put options by funds: $2.89M

10% more capital invested

Capital invested by funds: $743M → $816M (+$73.4M)

4% less funds holding

Funds holding: 153147 (-6)

5.14% less ownership

Funds ownership: 130.28%125.13% (-5.1%)

13% less first-time investments, than exits

New positions opened: 27 | Existing positions closed: 31

18% less repeat investments, than reductions

Existing positions increased: 45 | Existing positions reduced: 55

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

Holders
147
Holders Change
-6
Holders Change %
-3.92%
% of All Funds
1.94%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
27
Increased
45
Reduced
55
Closed
31
Calls
$5.28M
Puts
$2.89M
Net Calls
+$2.39M
Net Calls Change
+$1.83M
Name Holding Trade Value Shares
Change
Change in
Stake
EC
1
EcoR1 Capital
California
$175M
FLAM
2
First Light Asset Management
Minnesota
$78.6M -$22.9M -1,094,009 -24%
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$54.9M +$2.23M +106,504 +4%
Morgan Stanley
4
Morgan Stanley
New York
$41.5M +$28.6M +1,365,204 +271%
BlackRock
5
BlackRock
New York
$39.7M -$8.16M -389,664 -18%
Vanguard Group
6
Vanguard Group
Pennsylvania
$34.1M +$423K +20,225 +1%
TCM
7
Tang Capital Management
California
$29.5M -$4.49M -214,274 -14%
UBS Group
8
UBS Group
Switzerland
$28.2M +$16.4M +782,226 +160%
Bank of America
9
Bank of America
North Carolina
$23.9M -$1.41M -67,160 -6%
Citigroup
10
Citigroup
New York
$23.2M -$518K -24,759 -2%
SI
11
Sofinnova Investments
California
$22.9M -$2.67M -127,671 -11%
S
12
Sanofi
France
$18.2M
State Street
13
State Street
Massachusetts
$18.2M -$831K -39,692 -5%
PAI
14
Palo Alto Investors
California
$18M -$4.35M -207,892 -20%
T. Rowe Price Associates
15
T. Rowe Price Associates
Maryland
$14.9M -$5.06M -241,910 -26%
Victory Capital Management
16
Victory Capital Management
Texas
$11.8M +$2.63M +125,655 +31%
WP
17
Woodline Partners
California
$11.1M -$6.07M -290,000 -37%
6CM
18
683 Capital Management
New York
$11.1M +$6.37M +304,373 +156%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$10.3M -$582K -27,809 -6%
Jacobs Levy Equity Management
20
Jacobs Levy Equity Management
New Jersey
$8.18M +$7.37M +351,960 +2,135%
Franklin Resources
21
Franklin Resources
California
$7.87M +$2.45K +117 +0%
N
22
Nuveen
North Carolina
$7.18M +$5.6M +267,522 +478%
SCM
23
Soleus Capital Management
Connecticut
$7.13M +$4.58M +218,988 +215%
Two Sigma Advisers
24
Two Sigma Advisers
New York
$6.45M +$467K +22,300 +8%
Goldman Sachs
25
Goldman Sachs
New York
$6.21M -$15.5K -742 -0.3%

ANAB Hedge Fund Activity: Q2 2025 in Review

147 of the 7,596 institutional investors tracked by Wall St. Rank reported a position in AnaptysBio (ANAB) for Q2 2025, worth a combined $816M — up 9.9% from $743M a quarter earlier.

Sellers outnumbered buyers: 31 funds closed out of ANAB and 27 opened new positions — a net loss of 4 holders — while 55 trimmed existing stakes and 45 added.

The largest buyer was Morgan Stanley, adding an estimated $28.6M. The largest seller was Fidelity Investments, cutting an estimated $38.4M.

  • 147 institutional investors held AnaptysBio (ANAB) as of Q2 2025, down from 153 in Q1 2025.
  • Funds reported $816M of AnaptysBio stock for Q2 2025, up 9.9% quarter-over-quarter.
  • 27 funds opened new AnaptysBio positions in Q2 2025 and 31 closed out, a net change of -4 holders.
  • The largest AnaptysBio buyer in Q2 2025 was Morgan Stanley, an estimated $28.6M added.
  • The largest AnaptysBio seller in Q2 2025 was Fidelity Investments, an estimated $38.4M sold.

Based on aggregated 13F filings for Q2 2025.