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AnaptysBio

135 hedge funds and large institutions have $469M invested in AnaptysBio in 2024 Q4 according to their latest regulatory filings, with 27 funds opening new positions, 50 increasing their positions, 35 reducing their positions, and 52 closing their positions.

New
Increased
Maintained
Reduced
Closed

43% more repeat investments, than reductions

Existing positions increased: 50 | Existing positions reduced: 35

5.04% more ownership

Funds ownership: 111.35%116.39% (+5%)

0% more funds holding in top 10

Funds holding in top 10: 22 (0)

16% less funds holding

Funds holding: 160135 (-25)

39% less call options, than puts

Call options by funds: $21M | Put options by funds: $34.3M

48% less first-time investments, than exits

New positions opened: 27 | Existing positions closed: 52

58% less capital invested

Capital invested by funds: $1.13B → $469M (-$658M)

Holders
135
Holders Change
-25
Holders Change %
-15.63%
% of All Funds
1.78%
Holding in Top 10
2
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.03%
New
27
Increased
50
Reduced
35
Closed
52
Calls
$21M
Puts
$34.3M
Net Calls
-$13.3M
Net Calls Change
-$4.85M
Name Holding Trade Value Shares
Change
Change in
Stake
EC
1
EcoR1 Capital
California
$104M +$1.9M +78,452 +1%
Fidelity Investments
2
Fidelity Investments
Massachusetts
$40.1M -$6.76M -278,939 -8%
BlackRock
3
BlackRock
New York
$33.7M +$8.92M +368,279 +17%
Vanguard Group
4
Vanguard Group
Pennsylvania
$24.4M +$3.48M +143,584 +8%
FFM
5
Fairmount Funds Management
Pennsylvania
$24.1M +$44M +1,816,466 New
FLSM
6
Frazier Life Sciences Management
California
$20.8M -$15.4M -635,470 -29%
TCM
7
Tang Capital Management
California
$17.6M
BCM
8
Boxer Capital Management
California
$17.2M +$31.5M +1,300,000 New
State Street
9
State Street
Massachusetts
$17M +$9.19M +379,573 +42%
CCM
10
Camber Capital Management
Massachusetts
$16.6M +$30.3M +1,250,000 New
T. Rowe Price Associates
11
T. Rowe Price Associates
Maryland
$12.2M +$45.8K +1,890 +0.2%
FLAM
12
First Light Asset Management
Minnesota
$11.5M -$1.92M -79,249 -8%
PAI
13
Palo Alto Investors
California
$11.2M
S
14
Sanofi
France
$10.9M +$19.9M +821,917 New
Geode Capital Management
15
Geode Capital Management
Massachusetts
$6.44M +$513K +21,196 +5%
WP
16
Woodline Partners
California
$6.42M +$608K +25,094 +5%
Goldman Sachs
17
Goldman Sachs
New York
$5.55M +$1.67M +68,742 +20%
SCM
18
Soleus Capital Management
Connecticut
$5.48M +$10M +414,000 New
5VM
19
5AM Venture Management
California
$4.74M
Franklin Resources
20
Franklin Resources
California
$4.69M
Two Sigma Investments
21
Two Sigma Investments
New York
$4.66M +$3.4M +140,457 +66%
Victory Capital Management
22
Victory Capital Management
Texas
$4.43M +$2.35M +97,200 +41%
Assenagon Asset Management
23
Assenagon Asset Management
Luxembourg
$4.39M -$3.48M -143,688 -30%
Two Sigma Advisers
24
Two Sigma Advisers
New York
$3.88M +$2.61M +107,800 +58%
Jennison Associates
25
Jennison Associates
New York
$3.56M +$103K +4,242 +2%

ANAB Hedge Fund Activity: Q4 2024 in Review

135 of the 7,592 institutional investors tracked by Wall St. Rank reported a position in AnaptysBio (ANAB) for Q4 2024, worth a combined $469M — down 58% from $1.13B a quarter earlier.

Sellers outnumbered buyers: 52 funds closed out of ANAB and 27 opened new positions — a net loss of 25 holders — while 35 trimmed existing stakes and 50 added.

The largest buyer was Fairmount Funds Management, opening a new position worth an estimated $44M. The largest seller was Mangrove Partners, exiting entirely with an estimated $23.1M sold.

  • 135 institutional investors held AnaptysBio (ANAB) as of Q4 2024, down from 160 in Q3 2024.
  • Funds reported $469M of AnaptysBio stock for Q4 2024, down 58% quarter-over-quarter.
  • 27 funds opened new AnaptysBio positions in Q4 2024 and 52 closed out, a net change of -25 holders.
  • The largest AnaptysBio buyer in Q4 2024 was Fairmount Funds Management, an estimated $44M added.
  • The largest AnaptysBio seller in Q4 2024 was Mangrove Partners, an estimated $23.1M sold.

Based on aggregated 13F filings for Q4 2024.