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AnaptysBio

153 hedge funds and large institutions have $743M invested in AnaptysBio in 2025 Q1 according to their latest regulatory filings, with 44 funds opening new positions, 44 increasing their positions, 43 reducing their positions, and 26 closing their positions.

New
Increased
Maintained
Reduced
Closed

150% more funds holding in top 10

Funds holding in top 10: 25 (+3)

69% more first-time investments, than exits

New positions opened: 44 | Existing positions closed: 26

58% more capital invested

Capital invested by funds: $469M → $743M (+$274M)

13.89% more ownership

Funds ownership: 116.39%130.28% (+14%)

13% more funds holding

Funds holding: 135153 (+18)

11% more call options, than puts

Call options by funds: $5.68M | Put options by funds: $5.12M

2% more repeat investments, than reductions

Existing positions increased: 44 | Existing positions reduced: 43

Holders
153
Holders Change
+18
Holders Change %
+13.33%
% of All Funds
2.05%
Holding in Top 10
5
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+150%
% of All Funds
0.07%
New
44
Increased
44
Reduced
43
Closed
26
Calls
$5.68M
Puts
$5.12M
Net Calls
+$558K
Net Calls Change
+$13.9M
Name Holding Trade Value Shares
Change
Change in
Stake
EC
1
EcoR1 Capital
California
$146M +$111K +6,646 +0.1%
FLAM
2
First Light Asset Management
Minnesota
$86.1M +$62.8M +3,764,720 +433%
Point72 Asset Management
3
Point72 Asset Management
Connecticut
$44M +$39.5M +2,368,370 New
BlackRock
4
BlackRock
New York
$40.5M -$6.2M -371,870 -15%
Fidelity Investments
5
Fidelity Investments
Massachusetts
$35.4M -$18.8M -1,125,082 -37%
TCM
6
Tang Capital Management
California
$28.7M +$3.57M +214,274 +16%
Vanguard Group
7
Vanguard Group
Pennsylvania
$28.2M -$5.45M -326,415 -18%
BCM
8
Boxer Capital Management
California
$24.2M
SI
9
Sofinnova Investments
California
$21.6M +$17.1M +1,027,106 +773%
Bank of America
10
Bank of America
North Carolina
$21.3M +$18.8M +1,126,010 +6,273%
Citigroup
11
Citigroup
New York
$19.9M +$17M +1,017,470 +1,892%
PAI
12
Palo Alto Investors
California
$19M +$2.95M +176,742 +21%
T. Rowe Price Associates
13
T. Rowe Price Associates
Maryland
$17M -$166K -9,926 -1%
State Street
14
State Street
Massachusetts
$16M -$7.09M -425,032 -33%
S
15
Sanofi
France
$15.3M
WP
16
Woodline Partners
California
$14.7M +$5.1M +305,950 +63%
CCM
17
Camber Capital Management
Massachusetts
$13.9M -$8.34M -500,000 -40%
Morgan Stanley
18
Morgan Stanley
New York
$9.38M +$4.82M +288,719 +134%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$9.13M +$76.2K +4,570 +0.9%
UBS Group
20
UBS Group
Switzerland
$9.11M +$7.57M +453,667 +1,239%
Victory Capital Management
21
Victory Capital Management
Texas
$7.56M +$1.2M +71,980 +22%
Citadel Advisors
22
Citadel Advisors
Florida
$6.93M +$3.32M +198,842 +114%
5VM
23
5AM Venture Management
California
$6.65M
Franklin Resources
24
Franklin Resources
California
$6.59M +$350 +21 +0%
Renaissance Technologies
25
Renaissance Technologies
New York
$6.3M +$2.43M +145,500 +75%

ANAB Hedge Fund Activity: Q1 2025 in Review

153 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in AnaptysBio (ANAB) for Q1 2025, worth a combined $743M — up 58% from $469M a quarter earlier.

Buyers outnumbered sellers: 44 funds opened new ANAB positions and 26 closed out — a net gain of 18 holders — while 44 added to existing stakes and 43 trimmed.

The largest buyer was First Light Asset Management, adding an estimated $62.8M. The largest seller was Fairmount Funds Management, exiting entirely with an estimated $24.1M sold.

  • 153 institutional investors held AnaptysBio (ANAB) as of Q1 2025, up from 135 in Q4 2024.
  • Funds reported $743M of AnaptysBio stock for Q1 2025, up 58% quarter-over-quarter.
  • 44 funds opened new AnaptysBio positions in Q1 2025 and 26 closed out, a net change of +18 holders.
  • The largest AnaptysBio buyer in Q1 2025 was First Light Asset Management, an estimated $62.8M added.
  • The largest AnaptysBio seller in Q1 2025 was Fairmount Funds Management, an estimated $24.1M sold.

Based on aggregated 13F filings for Q1 2025.