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AnaptysBio

179 hedge funds and large institutions have $1.42B invested in AnaptysBio in 2025 Q4 according to their latest regulatory filings, with 37 funds opening new positions, 51 increasing their positions, 64 reducing their positions, and 24 closing their positions.

New
Increased
Maintained
Reduced
Closed

54% more first-time investments, than exits

New positions opened: 37 | Existing positions closed: 24

45% more capital invested

Capital invested by funds: $980M → $1.42B (+$443M)

8% more funds holding

Funds holding: 166179 (+13)

7.11% less ownership

Funds ownership: 113.12%106.02% (-7.1%)

14% less call options, than puts

Call options by funds: $20.8M | Put options by funds: $24.2M

20% less funds holding in top 10

Funds holding in top 10: 54 (-1)

20% less repeat investments, than reductions

Existing positions increased: 51 | Existing positions reduced: 64

Holders
179
Holders Change
+13
Holders Change %
+7.83%
% of All Funds
2.18%
Holding in Top 10
4
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-20%
% of All Funds
0.05%
New
37
Increased
51
Reduced
64
Closed
24
Calls
$20.8M
Puts
$24.2M
Net Calls
-$3.37M
Net Calls Change
+$2.37M
Name Holding Trade Value Shares
Change
Change in
Stake
EC
1
EcoR1 Capital
California
$382M
Point72 Asset Management
2
Point72 Asset Management
Connecticut
$93.7M -$13M -332,638 -15%
BlackRock
3
BlackRock
New York
$84.1M +$472K +12,106 +0.7%
Vanguard Group
4
Vanguard Group
Pennsylvania
$74.9M +$2.61M +67,048 +5%
TCM
5
Tang Capital Management
California
$64.6M -$60.5K -1,552 -0.1%
State Street
6
State Street
Massachusetts
$51.1M +$7.02M +180,042 +21%
Morgan Stanley
7
Morgan Stanley
New York
$50.2M -$20.3M -521,696 -34%
S
8
Sanofi
France
$39.8M
Millennium Management
9
Millennium Management
New York
$39.4M -$27.5M -705,659 -46%
PAI
10
Palo Alto Investors
California
$33.5M +$644K +16,512 +2%
D.E. Shaw & Co
11
D.E. Shaw & Co
New York
$32.5M +$12.5M +320,928 +92%
6CM
12
683 Capital Management
New York
$31.4M +$3.94M +101,093 +18%
FLAM
13
First Light Asset Management
Minnesota
$31.3M -$13.4M -343,923 -35%
Arrowstreet Capital
14
Arrowstreet Capital
Massachusetts
$27.1M +$7.38M +189,286 +51%
WP
15
Woodline Partners
California
$24.3M
Geode Capital Management
16
Geode Capital Management
Massachusetts
$22.8M -$161K -4,132 -0.9%
AAA
17
Affinity Asset Advisors
New York
$21.6M +$17.3M +444,692 New
Goldman Sachs
18
Goldman Sachs
New York
$19.3M +$2.69M +69,094 +21%
Two Sigma Advisers
19
Two Sigma Advisers
New York
$17.3M -$663K -17,000 -5%
N
20
Nuveen
North Carolina
$15.4M -$880K -22,586 -7%
Federated Hermes
21
Federated Hermes
Pennsylvania
$14.5M +$4.14M +106,089 +55%
SI
22
Sofinnova Investments
California
$13.9M +$1.3M +33,422 +13%
Two Sigma Investments
23
Two Sigma Investments
New York
$12.4M +$8.38K +215 +0.1%
Voloridge Investment Management
24
Voloridge Investment Management
Florida
$11.1M +$8.57M +219,816 +2,358%
Ensign Peak Advisors
25
Ensign Peak Advisors
Utah
$10.4M